Epicardial fat thickness correlates with coronary in-stent restenosis in patients with acute myocardial infarction

Autor: Julio O. Cabrera-Rego, Raúl A. Escobar-Torres, Juan D. Parra-Jiménez, Juan Valiente-Mustelier
Rok vydání: 2019
Předmět:
Bare-metal stent
Male
medicine.medical_specialty
medicine.medical_treatment
Coronary Artery Disease
030204 cardiovascular system & hematology
Sensitivity and Specificity
Coronary Restenosis
03 medical and health sciences
0302 clinical medicine
Percutaneous Coronary Intervention
Restenosis
Internal medicine
Medicine
ST segment
Humans
Pharmacology (medical)
In patient
030212 general & internal medicine
Myocardial infarction
Prospective Studies
Prospective cohort study
Aged
General Environmental Science
business.industry
General Engineering
Percutaneous coronary intervention
Middle Aged
medicine.disease
Epicardial fat
Treatment Outcome
Adipose Tissue
Echocardiography
Cardiology
ST Elevation Myocardial Infarction
General Earth and Planetary Sciences
Female
Stents
Cardiology and Cardiovascular Medicine
business
Pericardium
Follow-Up Studies
Zdroj: Clínica e Investigación en Arteriosclerosis (English Edition). 31:49-55
ISSN: 2529-9123
DOI: 10.1016/j.artere.2019.03.002
Popis: To determine the relation between epicardial fat thickness and coronary in-stent restenosis in patients with acute myocardial infarction and percutaneous coronary intervention.A prospective study was conducted, which included 129 patients (67.3% male, mean age 62.9±10 years) with ST segment elevation acute myocardial infarction undergoing primary percutaneous coronary intervention with bare metal stent. Patients were divided in two groups according to the presence (n=21) or not (n=108) of in-stent restenosis during one year follow-up.Epicardial fat was significantly thicker in patients with coronary in-stent restenosis (5.51±1.6 vs 4.14±2.0mm, p=0.006). A proportionally and significantly thicker epicardial fat was found according to the increase in coronary disease severity (3.3±0.9mm vs 4.3±1.8mm vs 4.7±2.3mm vs 6.7±2.2mm, for type A, B1, B2 and C lesions, respectively, p=0.001) and number of vessels (3.07±1.2mm vs 4.92±1.8mm vs 5.43±2.2mm, for one, two and three vessels disease, respectively, p0.0001). Epicardial fat thickness ≥4.7mm had 75.0% sensibility and 69.0% specificity for predicting restenosis (AUC=0.737).Echocardiographic evaluation of epicardial fat thickness could identify those patients with acute myocardial infarction with greater probabilities of in-stent restenosis after percutaneous coronary intervention.
Databáze: OpenAIRE
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