Epicardial fat thickness correlates with coronary in-stent restenosis in patients with acute myocardial infarction
Autor: | Julio O. Cabrera-Rego, Raúl A. Escobar-Torres, Juan D. Parra-Jiménez, Juan Valiente-Mustelier |
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Rok vydání: | 2019 |
Předmět: |
Bare-metal stent
Male medicine.medical_specialty medicine.medical_treatment Coronary Artery Disease 030204 cardiovascular system & hematology Sensitivity and Specificity Coronary Restenosis 03 medical and health sciences 0302 clinical medicine Percutaneous Coronary Intervention Restenosis Internal medicine Medicine ST segment Humans Pharmacology (medical) In patient 030212 general & internal medicine Myocardial infarction Prospective Studies Prospective cohort study Aged General Environmental Science business.industry General Engineering Percutaneous coronary intervention Middle Aged medicine.disease Epicardial fat Treatment Outcome Adipose Tissue Echocardiography Cardiology ST Elevation Myocardial Infarction General Earth and Planetary Sciences Female Stents Cardiology and Cardiovascular Medicine business Pericardium Follow-Up Studies |
Zdroj: | Clínica e Investigación en Arteriosclerosis (English Edition). 31:49-55 |
ISSN: | 2529-9123 |
Popis: | To determine the relation between epicardial fat thickness and coronary in-stent restenosis in patients with acute myocardial infarction and percutaneous coronary intervention.A prospective study was conducted, which included 129 patients (67.3% male, mean age 62.9±10 years) with ST segment elevation acute myocardial infarction undergoing primary percutaneous coronary intervention with bare metal stent. Patients were divided in two groups according to the presence (n=21) or not (n=108) of in-stent restenosis during one year follow-up.Epicardial fat was significantly thicker in patients with coronary in-stent restenosis (5.51±1.6 vs 4.14±2.0mm, p=0.006). A proportionally and significantly thicker epicardial fat was found according to the increase in coronary disease severity (3.3±0.9mm vs 4.3±1.8mm vs 4.7±2.3mm vs 6.7±2.2mm, for type A, B1, B2 and C lesions, respectively, p=0.001) and number of vessels (3.07±1.2mm vs 4.92±1.8mm vs 5.43±2.2mm, for one, two and three vessels disease, respectively, p0.0001). Epicardial fat thickness ≥4.7mm had 75.0% sensibility and 69.0% specificity for predicting restenosis (AUC=0.737).Echocardiographic evaluation of epicardial fat thickness could identify those patients with acute myocardial infarction with greater probabilities of in-stent restenosis after percutaneous coronary intervention. |
Databáze: | OpenAIRE |
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