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The assessment of heavy metals (lead and mercury) and by-product (sulphur) on fried food sold by roadside food vendors in Calabar, Nigeria were investigated. The food samples which were covered and uncovered after frying were obtained randomly from 20 street food vendors. The food samples were obtained from 10 busy roads and 10 non- busy roads in Calabar, Nigeria. The busy roads were those roads that recorded more than 20 cars per minute, while the non-busy roads recorded less than 10 cars per minute. The result showed that the busy roads had significant (P |