Brain correlates of recognition of communicative interactions from biological motion in schizophrenia
| Autor: | Małgorzata Wordecha, Bartosz Kossowski, Łukasz Okruszek, Junghee Lee, Michał Jarkiewicz, Artur Marchewka |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Motion Perception 050105 experimental psychology Young Adult 03 medical and health sciences 0302 clinical medicine Social cognition Connectome medicine Humans Interpersonal Relations 0501 psychology and cognitive sciences Applied Psychology Cerebral Cortex Neural correlates of consciousness Communication 05 social sciences Psychophysiological Interaction Superior temporal sulcus Middle Aged medicine.disease Magnetic Resonance Imaging Psychiatry and Mental health Pattern Recognition Visual Social Perception Mentalization Schizophrenia Female Psychology 030217 neurology & neurosurgery Biological motion Mirroring Cognitive psychology |
| Zdroj: | Psychological Medicine. 48:1862-1871 |
| ISSN: | 1469-8978 0033-2917 |
| DOI: | 10.1017/s0033291717003385 |
| Popis: | BackgroundRecognition of communicative interactions is a complex social cognitive ability which is associated with a specific neural activity in healthy individuals. However, neural correlates of communicative interaction processing from whole-body motion have not been known in patients with schizophrenia (SCZ). Therefore, the current study aims to examine the neural activity associated with recognition of communicative interactions in SCZ by using displays of the dyadic interactions downgraded to minimalistic point-light presentations.MethodsTwenty-six healthy controls (HC) and 25 SCZ were asked to judge whether two agents presented only by point-light displays were communicating or acting independently. Task-related activity and functional connectivity of brain structures were examined with General Linear Model and Generalized Psychophysiological Interaction approach, respectively.ResultsHC were significantly more efficient in recognizing each type of action than SCZ. At the neural level, the activity of the right posterior superior temporal sulcus (pSTS) was observed to be higher in HC compared with SCZ for communicativev.individual action processing. Importantly, increased connectivity of the right pSTS with structures associated with mentalizing (left pSTS) and mirroring networks (left frontal areas) was observed in HC, but not in SCZ, during the presentation of social interactions.ConclusionUnder-recruitment of the right pSTS, a structure known to have a pivotal role in social processing, may also be of importance for higher-order social cognitive deficits in SCZ. Furthermore, decreased task-related connectivity of the right pSTS may result in reduced use of additional sources of information (for instance motor resonance signals) during social cognitive processing in schizophrenia. |
| Databáze: | OpenAIRE |
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