Insulin and cardiovascular risk factors in newly diagnosed diabetes mellitus patients
| Autor: | Suzanna Ndraha, Wilfried Herdin Sibuea |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
lcsh:R5-920 Triglyceride business.industry Insulin medicine.medical_treatment Hypertriglyceridemia nutritional and metabolic diseases General Medicine medicine.disease chemistry.chemical_compound Blood pressure Waist–hip ratio Endocrinology Insulin resistance chemistry Internal medicine Diabetes mellitus Medicine lipids (amino acids peptides and proteins) business lcsh:Medicine (General) Body mass index |
| Zdroj: | Medical Journal of Indonesia, Vol 7, Iss 2 (1998) |
| ISSN: | 2252-8083 0853-1773 |
| Popis: | The purpose of this study is to assess the insulin resistance and cardiovascular risk factors in newly diagnosed NIDDM compared with normal control subjects. Thirty subjects with newly diagnosed NIDDM and 30 healthy control subjects, with no family history of NIDDIVI, matched for age, gender and body mass index participated in this study. Oral glucose tolerance test was performed to measure the insulin response to oral glucose. In both groups, waist to hip ratio, systolic and diastolic blood pressure were measured. Venous blood samples were taken at fasting for insulin, glucose, HbAlc, triglyceride, total cholesterol, LDL cholesterol and HDL cholesterol determinations. Several characteristics of metabolic abnormalities distinguished the newly diagnosed NIDDM from control subjects. The type-2 diabetes subjects had significantly higher systolic blood pressure, plasma glucose, glycosilated hemoglobin, triglycaride, total cholesterol and LDL cholesterol levels compared with controls, but during OGTT, the insulin levels and insulin to glucose ratio at 30-min and I 20-min were lower in newly diabetes subjects. In this shrdy we found the presence of insulin deficiency and cardiovascular risk factors such as higher systolic blood pressure, hypertriglyceridemia, hypercholesterolemia in newly diagnosed NIDDM but there was no correlation between insulin with those risk factors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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