Ventilation efficiency to exercise in patients with cystic fibrosis

Autor: Asterios Kampouras, Vasiliki Georgopoulou, Fotis Kirvassilis, John Tsanakas, Helge Hebestreit, Vasiliki Avramidou, Elpis Hatziagorou
Rok vydání: 2019
Předmět:
Zdroj: Pediatric pulmonology. 54(10)
ISSN: 1099-0496
Popis: INTRODUCTION Exercise ventilation efficiency index in cardiopulmonary exercise testing (CPET) is elevated in patients with heart failure providing useful information on disease progression and prognosis. Few data, however, exist for ventilation efficiency index among cystic fibrosis (CF) patients. AIMS To assess ventilation efficiency index (ΔVE/ΔVCO2 or V'E/V'CO2 slope) and intercept of ventilation (VE-intercept) in CF patients with mild, moderate, and severe cystic fibrosis (CF) lung disease. To assess possible correlations with ventilation inhomogeneity and structural damages as seen on high resolution computed tomography (HRCT). METHODS CF patients with mild (FEV1 > 80%, n = 47), moderate (60%
Databáze: OpenAIRE