Ventilation efficiency to exercise in patients with cystic fibrosis
Autor: | Asterios Kampouras, Vasiliki Georgopoulou, Fotis Kirvassilis, John Tsanakas, Helge Hebestreit, Vasiliki Avramidou, Elpis Hatziagorou |
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Rok vydání: | 2019 |
Předmět: |
Pulmonary and Respiratory Medicine
Spirometry Adult Male medicine.medical_specialty High-resolution computed tomography Respiratory rate Adolescent Cystic Fibrosis Cystic fibrosis Young Adult Internal medicine Medicine Humans Respiratory system Child Exercise medicine.diagnostic_test business.industry VO2 max Carbon Dioxide medicine.disease Oxygen Heart failure Pediatrics Perinatology and Child Health Breathing Cardiology Female business Pulmonary Ventilation |
Zdroj: | Pediatric pulmonology. 54(10) |
ISSN: | 1099-0496 |
Popis: | INTRODUCTION Exercise ventilation efficiency index in cardiopulmonary exercise testing (CPET) is elevated in patients with heart failure providing useful information on disease progression and prognosis. Few data, however, exist for ventilation efficiency index among cystic fibrosis (CF) patients. AIMS To assess ventilation efficiency index (ΔVE/ΔVCO2 or V'E/V'CO2 slope) and intercept of ventilation (VE-intercept) in CF patients with mild, moderate, and severe cystic fibrosis (CF) lung disease. To assess possible correlations with ventilation inhomogeneity and structural damages as seen on high resolution computed tomography (HRCT). METHODS CF patients with mild (FEV1 > 80%, n = 47), moderate (60% |
Databáze: | OpenAIRE |
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