Alisma orientale: Ethnopharmacology, Phytochemistry and Pharmacology of an Important Traditional Chinese Medicine
Autor: | Lu-Ping Qin, Pu Jiang, Yuanbin Zhang, Cheng-Jian Zheng, Zhiheng Shu, Ling Chen, Khalid Rahman |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Phytochemistry Alismataceae ved/biology.organism_classification_rank.species Molecular Conformation Traditional Chinese medicine Pharmacology law.invention Terpene Structure-Activity Relationship 03 medical and health sciences 0302 clinical medicine Urolithiasis Polysaccharides law Drug Discovery Alisma Humans Immunologic Factors Alisma orientale Medicine Chinese Traditional Diuretics Flavonoids Nephritis biology Traditional medicine Plant Extracts Terpenes ved/biology Liver Diseases nutritional and metabolic diseases General Medicine biology.organism_classification 030104 developmental biology Complementary and alternative medicine 030220 oncology & carcinogenesis Medicinal herbs Phytotherapy Rhizome |
Zdroj: | The American Journal of Chinese Medicine. 44:227-251 |
ISSN: | 1793-6853 0192-415X |
Popis: | Alisma orientale (Sam.) Juzep. (Alismataceae) is a traditional and famous Chinese medicinal herb. Its rhizomes, which possess versatile bioactivities, are commonly used to treat oliguria, edema, gonorrhea with turbid urine, leukorrhea, diarrhea and dizziness. Approximately 120 compounds have been isolated from A. orientale. Terpenoids have been identified as A. orientale’s characteristic constituents, which include protostane triterpenoids and guaiane sesquiterpenoids. The traditional medical uses of A. orientale in TCM have been evaluated in modern pharmacological studies, which have shown that A. orientale and its active constituents exhibit a wide range of bioactivities, such as diuretic, anti-urolithiatic, antinephritic, anti-atherosclerotic, immunomodulatory, and hepatoprotective activities. The medicinal potential of A. orientale makes it an ideal candidate for new drug development. Further studies are still required to identify its bioactive constituents, and elucidate the structure–activity relationship and detailed mechanisms of action. Additionally, the use of the other medicinal parts of A. orientale may reduce resource waste and afford novel secondary metabolites. |
Databáze: | OpenAIRE |
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