The Relationship Between Nasal Mucociliary Clearance Time and the Degree of Smoking Dependence in Smokers with Obstructive Sleep Apnea Syndrome
| Autor: | Fevzi Solmaz, Tekin Yildiz, Süay Özmen, Çağla Çapkur, Özlem Şengören Dikiş, Seyhan Dülger, Sündüs Gençay |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine 2019-20 coronavirus outbreak medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Mucociliary clearance Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Gastroenterology Internal medicine medicine Humans Nicotine dependence Sleep Apnea Obstructive Smokers business.industry Smoking Middle Aged medicine.disease respiratory tract diseases Obstructive sleep apnea Nasal Mucosa Mucociliary Clearance Case-Control Studies Female Analysis of variance business smoking obstructive sleep apnea nasal mucociliary clearance time saccharine test |
| Zdroj: | Advances in Respiratory Medicine; Volume 89; Issue 4; Pages: 353-358 |
| ISSN: | 2543-6031 |
| DOI: | 10.5603/arm.a2021.0069 |
| Popis: | Introduction: The aim of this study was to investigate the relationship between nasal mucociliary clearance time (NMCT), degree of smoking dependence, cumulative smoking burden and OSAS severity in smokers. Material and methods: 123 patients (Group 1) with OSAS and 92 healthy controls (Group 2) were included in the study. Group 1 was divided into smokers (Group 1a) and non-smokers (Group 1b). In Group 1a, cumulative smoking burden and Fagerström nicotine dependence test (FNDT) were questioned. Saccharin test was applied to Groups 1 and 2. Student-t, Mann-Whitney-U, Anova, Kruskal-Wallis tests were used to compare the means. Results: NMCT was higher in Group 1 than Group 2 (p = 0.005). The duration of NMCT was higher in Group 1A than Group 1B (p = 0.002). In Group 1a, NMCT values of mild and moderate OSAS patients were longer than in Group 1b (p = 0.02, p = 0.01, respectively). NMCT values of patients with mild dependence were shorter than those with moderate or severe dependence (p = 0.032, p < 0.001, respectively). Conclusion: Mucociliary clearance time was higher in smokers with OSAS than non-smokers. While OSAS has a negative effect on mucociliary clearance, smoking also exacerbates the condition. |
| Databáze: | OpenAIRE |
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