Pellagra, an Almost‐Forgotten Differential Diagnosis of Chronic Diarrhea: More Prevalent Than We Think
Autor: | Shanjin Cao, Kristen Cestodio, Xiaodan Wang |
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Rok vydání: | 2019 |
Předmět: |
Diarrhea
Male Niacinamide Pediatrics medicine.medical_specialty 030309 nutrition & dietetics Medicine (miscellaneous) Dermatitis Niacin Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Chronic diarrhea Risk Factors Pellagra Prevalence Humans Medicine Dementia Skin Aged 80 and over 0303 health sciences Treated patient Nutrition and Dietetics business.industry medicine.disease Alcoholism Treatment Outcome Vitamin B Complex Etiology 030211 gastroenterology & hepatology medicine.symptom Differential diagnosis business |
Zdroj: | Nutrition in Clinical Practice. 35:860-863 |
ISSN: | 1941-2452 0884-5336 |
DOI: | 10.1002/ncp.10418 |
Popis: | Pellagra, caused by vitamin B3 (niacin) deficiency, is traditionally described as dermatitis, diarrhea, dementia (3D), and even death (4D) syndrome if not recognized and treated promptly. Although full-blown pellagra with all 3D features has become rare, pellagra still exists, especially in high-risk populations, which is actually more prevalent than we think. We report that a recently treated patient with the full spectrum of 3D clinical features of pellagra presents as chronic diarrhea of unknown etiology for 1 year. It reminds us that keeping a high index of suspicion and maintaining a broad differential diagnosis are critical for recognition and management of this potentially fatal but treatable condition. |
Databáze: | OpenAIRE |
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