Pellagra, an Almost‐Forgotten Differential Diagnosis of Chronic Diarrhea: More Prevalent Than We Think

Autor: Shanjin Cao, Kristen Cestodio, Xiaodan Wang
Rok vydání: 2019
Předmět:
Zdroj: Nutrition in Clinical Practice. 35:860-863
ISSN: 1941-2452
0884-5336
DOI: 10.1002/ncp.10418
Popis: Pellagra, caused by vitamin B3 (niacin) deficiency, is traditionally described as dermatitis, diarrhea, dementia (3D), and even death (4D) syndrome if not recognized and treated promptly. Although full-blown pellagra with all 3D features has become rare, pellagra still exists, especially in high-risk populations, which is actually more prevalent than we think. We report that a recently treated patient with the full spectrum of 3D clinical features of pellagra presents as chronic diarrhea of unknown etiology for 1 year. It reminds us that keeping a high index of suspicion and maintaining a broad differential diagnosis are critical for recognition and management of this potentially fatal but treatable condition.
Databáze: OpenAIRE