Solvent-Detergent Plasma for the Treatment of Thrombotic Microangiopathies: A Canadian Tertiary Care Centre Experience
| Autor: | Lauren J. Lee, Paul R. Yenson, Leslie N. Zypchen, Gayatri M. Sreenivasan, Kimberley L.S. Ambler, Kristine J. Roland |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Canada medicine.medical_specialty Detergents Thrombotic thrombocytopenic purpura 030204 cardiovascular system & hematology Lung injury Gastroenterology Tertiary care Tertiary Care Centers Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine Atypical hemolytic uremic syndrome Blood plasma medicine Humans Solvent detergent plasma Aged Aged 80 and over Thrombotic Microangiopathies business.industry Hematology Middle Aged medicine.disease Tolerability Solvents Female Fresh frozen plasma business 030215 immunology |
| Zdroj: | Transfusion and Apheresis Science. 57:233-235 |
| ISSN: | 1473-0502 |
| DOI: | 10.1016/j.transci.2018.02.005 |
| Popis: | Solvent detergent-treated plasma (SDP) is a pathogen-inactivated blood plasma, which in comparison to frozen plasma is associated with lower rates of allergic reaction, transfusion-associated lung injury, and viral transmission. SDP has been available in Canada since 2012. Data on SDP use in Canada remains limited. We present a review of subjects receiving SDP at a large tertiary care centre primarily for thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, demonstrating the tolerability and safety of SDP. |
| Databáze: | OpenAIRE |
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