Double-blind comparison of the efficacy of extradural diamorphine, extradural phenoperidine and i.m. diamorphine following caesarean section
| Autor: | D. J. MacRae, L. M. Burrow, M. K. Milne, S. Munishankrappa, I.S. Grant |
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| Rok vydání: | 1987 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors medicine.medical_treatment Analgesic Injections Epidural Injections Intramuscular Double blind Double-Blind Method Pregnancy Medicine Humans Caesarean section Pain Measurement Phenoperidine Pain Postoperative business.industry Cesarean Section Surgery Heroin Anesthesiology and Pain Medicine Anesthesia Rapid onset Morphine Female business medicine.drug |
| Zdroj: | British journal of anaesthesia. 59(3) |
| ISSN: | 0007-0912 |
| Popis: | A randomized, double-blind study of the efficacy, duration of action and side effects of three analgesic regimens following Caesarean section is described. Patients received i.m. diamorphine 5 mg, extradural phenoperidine 2 mg or extradural diamorphine 5 mg. Analgesia was of rapid onset in all groups, as judged by reductions in linear analogue pain scores and rank pain scores. Time to next analgesia was significantly greater after extradural phenoperidine (5.96 h) and extradural diamorphine (8.39 h) than after i.m. diamorphine (3.40 h) (P less than 0.001). Itching was reported on direct questioning by 50% of patients in the extradural groups. No serious side effects were reported. Factors affecting the disposition of extradurally administered diamorphine are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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