Assessment of problematic severe asthma in children
| Autor: | Carlsen, K. C. L., Hedlin, G., Bush, A., Wennergren, G., de Benedictis, F. M., De Jongste, J. C., Baraldi, E., Pedroletti, C., Barbato, A., Malmstrom, K., Pohunek, P., Pedersen, S., Piacentini, G. L., Middelveld, R. J. M., Carlsen, K. H., Grp, Psaci |
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| Přispěvatelé: | Pediatrics |
| Rok vydání: | 2011 |
| Předmět: |
Pulmonary and Respiratory Medicine
Severe asthma medicine.medical_specialty diagnosis Comorbidity Severity of Illness Index children Treatment plan medicine Humans Anti-Asthmatic Agents Child Intensive care medicine Rhinitis Asthma business.industry medicine.disease Respiratory Function Tests Clinical Practice Treatment Outcome Lung disease Physical therapy Bronchial Hyperreactivity business |
| Zdroj: | Carlsen, K C L, Hedlin, G, Bush, A, Wennergren, G, de Benedictis, F M, De Jongste, J C, Baraldi, E, Pedroletti, C, Barbato, A, Malmstrom, K, Pohunek, P, Pedersen, S, Piacentini, G L, Middelveld, R J M, Carlsen, K H & Grp, P 2011, ' Assessment of problematic severe asthma in children ', European Respiratory Journal, vol. 37, no. 2, pp. 432-440 . https://doi.org/10.1183/09031936.00091410 European Respiratory Journal, 432-440. European Respiratory Society STARTPAGE=432;ENDPAGE=440;ISSN=0903-1936;TITLE=European Respiratory Journal |
| ISSN: | 0903-1936 |
| DOI: | 10.1183/09031936.00091410 |
| Popis: | Assessment of problematic severe asthma in children should be performed in a step-wise manner to ensure an optimal approach. A four-step assessment scheme is proposed. First, a full diagnostic work-up is performed to exclude other diseases which mimic asthma. Secondly, a multi-disciplinary assessment is performed to identify issues that may need attention, including comorbidities. Thirdly, the pattern of inflammation is assessed, and finally steroid responsiveness is documented. Based upon these four steps an optimal individualised treatment plan is developed. In this article the many gaps in our current knowledge in all these steps are highlighted, and recommendations for current clinical practice and future research are made. The lack of good data and the heterogeneity of problematic severe asthma still limit our ability to optimise the management on an individual basis in this small, but challenging group of patients. |
| Databáze: | OpenAIRE |
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