Impact of colorectal cancer screening on cancer-specific mortality in Europe: A systematic review
| Autor: | Andrea Gini, Erik E.L. Jansen, Nadine Zielonke, Reinier G.S. Meester, Carlo Senore, Ahti Anttila, Nereo Segnan, Dominika Novak Mlakar, Harry J. de Koning, Iris Lansdorp-Vogelaar, Piret Veerus, Sirpa Heinävaara, Tytti Sarkeala, Marcell Csanádi, Janos Pitter, György Széles, Zoltán Vokó, Silvia Minozzi, Marjolein van Ballegooijen, Inge Driesprong - de Kok, Eveline Heijnsdijk, Erik Jansen, Harry de Koning, Iris Lansdorp – Vogelaar, Nicolien van Ravesteyn, Urska Ivanus, Katja Jarm, Maja Primic-Žakelj, Martin McKee, Jennifer Priaulx |
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| Přispěvatelé: | Public Health |
| Jazyk: | angličtina |
| Předmět: |
0301 basic medicine
Cancer Research Colorectal cancer MEDLINE Colonoscopy Cochrane Library 03 medical and health sciences 0302 clinical medicine SDG 3 - Good Health and Well-being medicine Humans Mortality Early Detection of Cancer medicine.diagnostic_test business.industry Fecal occult blood Sigmoidoscopy medicine.disease Prognosis 3. Good health Clinical trial Europe Survival Rate 030104 developmental biology Oncology 030220 oncology & carcinogenesis Observational study business Colorectal Neoplasms Demography |
| Zdroj: | European Journal of Cancer European Journal of Cancer, 127, 224-235. Elsevier Ltd. |
| ISSN: | 0959-8049 |
| DOI: | 10.1016/j.ejca.2019.12.014 |
| Popis: | Background: Populations differ with respect to their cancer risk and screening preferences, which may influence the performance of colorectal cancer (CRC) screening programs. This review aims to systematically compare the mortality effect of CRC screening across European regions. Methods: Six databases including Embase, Medline, Web of Science, PubMed publisher, Google Scholar and Cochrane Library were searched for relevant studies published before March 2018. Bibliographic searches were conducted to select studies assessing the effect of various screening tests (guaiac fecal occult blood test [gFOBT]; flexible sigmoidoscopy [FS]; fecal immunochemical test [FIT] and colonoscopy) on CRC mortality in Europe (PROSPERO protocol: CRD42016042433). Abstract reviewing, data extraction and risk of bias assessment were conducted independently by two reviewers. Results: A total of 18 studies were included; of which, 11 were related to gFOBT, 4 to FS, 2 to FIT and 1 to colonoscopy; 8 were randomised clinical trials, and 10, observational studies, and an approximately equal number of studies represented Northern, Western and Southern European regions. Among individuals invited to screening, CRC mortality reductions varied from 8% to 16% for gFOBT and from 21% to 30% for FS. When studies with a high risk of bias were considered, ranges were more extensive. The estimated effectiveness of gFOBT and FS screening appeared similar across different European regions. Conclusions: CRC mortality impact of inviting individuals with similar adopted screening strategies (gFOBT or FS) may be consistent across several European settings. |
| Databáze: | OpenAIRE |
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