Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy

Autor: Chikako Watanabe, Nao Sugihara, Masaaki Higashiyama, Rina Tanemoto, Michio Kubota, Hisato Terada, Shunsuke Komoto, Ryota Hokari, Masami Shinozaki, Takeshi Takajo, Shigeaki Nagao, Kengo Tomita, Shin Nishii, Daisuke Miyagishima, Akinori Wada, Shigeyoshi Soga, Yoshinori Hanawa, Nobuaki Gotoh, Kazuhiko Shirakabe, Akinori Mizoguchi, Hideki Ueno, Hirotaka Furuhashi, Suguru Ito, Kazuki Horiuchi, Soichiro Miura, Akihiko Nakagawa
Rok vydání: 2019
Předmět:
Zdroj: Internal Medicine
ISSN: 1349-7235
0918-2918
Popis: We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn's disease (CD). PLE was supposedly induced by both intestinal erosion and thrombosis-related lymphangiectasia, which was histologically proven in his surgically-resected ileal stenosis. Elemental diet and anti-TNFα agent improved his hypoalbuminemia after surgery. The rarity of the simultaneous coexistence of SMV obstruction and PLE and the precedence of these complications over typical abdominal symptoms of CD made the clinical course complex.
Databáze: OpenAIRE