Comparative Assessment of the Treatment of Type 2 Diabetes Mellitus
| Autor: | Vesna Čapkun, Sanda Tesanović, Djurdja Dovzak-Kokić, Maja Radman, Slaven Kokić |
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| Rok vydání: | 2002 |
| Předmět: | |
| Zdroj: | Annals of Saudi Medicine. 22:163-166 |
| ISSN: | 0975-4466 0256-4947 |
| DOI: | 10.5144/0256-4947.2002.163 |
| Popis: | Background: The objective of the study was to estimate the most successful way of treating patients with type 2 diabetes mellitus. Patients and Methods: A total of 87 patients with type 2 diabetes mellitus were selected for a three-month study. The patients were divided into three groups comprising 29 patients in each group, based upon the treatment regimen. Group 1 (BMI 32.3±3.6 kg/m 2 ) was treated with glimepiride and metformin; group 2 (BMI 27.9±3.9) was treated with daily doses of insulin mixture 30/70 and bed-time NPH insulin; and group 3 (BMI 30.2±4.8) was treated with a combination of three daily doses of lispo and metformin. The groups did not differ significantly in terms of sex and age. Results: Initially, there were significant statistical differences in HbA1c (P=0.035) between the three groups (9,21%±1.72%; 9.21%±1.54%; and 10,0%±1.73%, respectively). After three months, there were no statistically significant differences in HbA1c (P=0.66) between the groups (8.52%±1.7%; 8.03%±1.05%; and 8.0%±0.63%, respectively). Decreases in HbA1c were significant in all groups, but most pronounced in patients treated with lispro and metformin (17% on average). Conclusion: The study results suggest the need for establishing guidelines on how to treat type 2 diabetics. Ann Saudi Med 2002;22(3-4):163-166. |
| Databáze: | OpenAIRE |
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