Second-Trimester Constituents of the Metabolic Syndrome and Pregnancy Outcome: An Observational Cohort Study
| Autor: | Jonas Ellerbrock, Esmee Hubers, Chahinda Ghossein-Doha, Veronique Schiffer, Robert-Jan Alers, Laura Jorissen, Jolijn van Neer, Maartje Zelis, Emma Janssen, Sabine Landewé-Cleuren, Annemie van Haarlem, Boris Kramer, Marc Spaanderman |
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| Přispěvatelé: | RS: GROW - R4 - Reproductive and Perinatal Medicine, Obstetrie & Gynaecologie, MUMC+: MA Med Staf Artsass Cardiologie (9), MUMC+: MA Arts Assistenten Obstetrie Gynaecologie (9), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, MUMC+: MA Medische Staf Obstetrie Gynaecologie (9), MUMC+: TPZ Diabetes Zorg (9), RS: MHeNs - R3 - Neuroscience, Kindergeneeskunde, MUMC+: MA Medische Staf Kindergeneeskunde (9) |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
obesity
hypertension BLOOD-PRESSURE DIAGNOSIS metabolic syndrome CLASSIFICATION Cohort Studies preeclampsia Pre-Eclampsia Pregnancy Risk Factors HYPERGLYCEMIA Humans PART 1 gestational diabetes dyslipidemia preterm birth RISK Nutrition and Dietetics Infant Newborn Pregnancy Outcome PROTEINURIA WOMEN DIABETES-MELLITUS ASSOCIATION Diabetes Gestational Diabetes Mellitus Type 2 Pregnancy Trimester Second Premature Birth Female Food Science |
| Zdroj: | Nutrients; Volume 14; Issue 14; Pages: 2933 Nutrients, 14(14):2933. Multidisciplinary Digital Publishing Institute (MDPI) |
| ISSN: | 2072-6643 |
| Popis: | Background: Gestational diabetes mellitus (GDM) increases the risk of type 2 diabetes mellitus and cardiovascular disease (CVD) in women in later life. In the general population, metabolic syndrome (MetS) shows identical associations. The aim of this study was to evaluate the association between GDM, constituents of MetS and pregnancy outcomes. Methods: Of 2041 pregnant women undergoing an oral glucose tolerance test (OGTT) between 22 and 30 weeks of gestation, data were collected to evaluate the constituents of MetS. Odds ratios (ORs) were calculated to determine the associations between MetS and pregnancy outcomes. Results: GDM and obesity did not affect the risk of fetal growth abnormalities (SGA/LGA), preterm birth or preeclampsia (PE). Hypertension significantly increased the risk of SGA (OR—1.59), PE (OR—3.14), and preterm birth |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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