Subcutaneous Phaeohyphomycosis Caused by Cladophialophora bantiana
| Autor: | Sean M. Hussey, Rita M. Gander, Mai P. Hoang, Paul M. Southern |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Antifungal Agents Biopsy Prednisolone medicine.medical_treatment Cladophialophora bantiana Pathology and Forensic Medicine Immunocompromised Host Ascomycota Recurrence Subcutaneous Phaeohyphomycosis medicine Dermatomycoses Humans Lupus Erythematosus Systemic Fluconazole Glucocorticoids African american Lupus erythematosus business.industry Traumatic implantation Immunosuppression General Medicine medicine.disease Medical Laboratory Technology Phaeohyphomycosis Female Itraconazole business |
| Zdroj: | Archives of Pathology & Laboratory Medicine. 129:794-797 |
| ISSN: | 1543-2165 0003-9985 |
| Popis: | Primary subcutaneous phaeohyphomycosis can rarely be caused by Cladophialophora bantiana, and we present the histologic and culture findings of such a case. A 32-year-old African American woman with systemic lupus erythematosus presented with a 2-year history of multiple, recurrent, tender, and ulcerated skin nodules with purulent drainage on her upper back. Histologic sections of the excision demonstrated features of phaeohyphomycosis. Culture findings were characteristic of C bantiana. Of interest, at age 10 she had sustained traumatic implantation of wood splinters into this area during a tornado, yet clinical symptoms of a subcutaneous infection did not manifest until she developed lupus erythematosus at age 27. Our case highlights the role of trauma and immunosuppression in the pathogenesis of subcutaneous phaeohyphomycosis. |
| Databáze: | OpenAIRE |
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