Catamenial epilepsy: hormonal aspects
| Autor: | Angelika Mohn, Giangennaro Coppola, Melissa Laus, Francesco Chiarelli, Pasquale Parisi, Alberto Verrotti |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
medicine.medical_specialty Exacerbation Adolescent DHEAS Endocrinology Diabetes and Metabolism media_common.quotation_subject medicine.medical_treatment Physiology Luteal phase Anovulatory cycle allopregnenolone androstenediol catamenial epilepsy dheas estrogens progesterone testosterone thdoc Epilepsy Young Adult Endocrinology Catamenial epilepsy THDOC Anticonvulsants Estrogens Female Humans Menstrual Cycle Neurotransmitter Agents Prevalence Progesterone Obstetrics and Gynecology Internal medicine Medicine Young adult Menstrual cycle media_common business.industry medicine.disease Diabetes and Metabolism Anticonvulsant business |
| Zdroj: | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 26(11) |
| ISSN: | 1473-0766 |
| Popis: | The term catamenial epilepsy is used to describe the cyclical occurrence of seizure exacerbations during particular phases of menstrual cycle in women with preexisting epilepsy. Recent investigations have demonstrated the existence of at least three patterns of catamenial seizure exacerbation: perimenstrual and periovulatory in ovulatory cycle and entire luteal phase in anovulatory cycle. Cyclical changes in the circulating levels of estrogens (proconvulsant) and progesterone (anticonvulsant) play a central role in the development of catamenial epilepsy. Also, variations in concentrations of antiepileptic drugs across the menstrual cycle may contribute to increased seizure susceptibility. A variety of approaches have been proposed for the treatment of catamenial epilepsy. |
| Databáze: | OpenAIRE |
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