Notes: Flavonols from Scurrula ferruginea Danser (Loranthaceae)
| Autor: | Didier Fontanel, Joël Boustie, Sophie Tomasi, Françoise Lohézic-Le Dévéhat |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Flavonoids
chemistry.chemical_classification Magnetic Resonance Spectroscopy Molecular Structure biology Molecular Conformation Ethyl acetate Glycoside Loranthaceae biology.organism_classification medicine.disease Quercitrin General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Flavonols chemistry Botany medicine Spectrophotometry Ultraviolet Scurrula ferruginea Quercetin Glioblastoma |
| Zdroj: | Zeitschrift für Naturforschung C. 57:1092-1096 |
| ISSN: | 1865-7125 0939-5075 |
| DOI: | 10.1515/znc-2002-11-1224 |
| Popis: | Three natural flavonols compounds have been isolated from the ethyl acetate fraction of Scurrula ferruginea Danser (Loranthaceae). Besides quercetin and quercitrin, an unusual flavonol glycoside 4″-O-acetylquercitrin was isolated. Structures were determined using spectroscopic methods including UV, NMR and HRMS-EI. The incidence of 4″-O-acetylquercitrin, not previously reported in the Loranthaceae, is discussed. Cytotoxic evaluation on four human cancer cell lines showed quercetin to be the most active with IC50 of 35 μм on U251 (human glioblastoma cells). |
| Databáze: | OpenAIRE |
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