Dipyridamole-induced adverse effects in myocardial perfusion scans: Dynamic evaluation
| Autor: | Nan-Jing Peng, Chin Hu, Wei-Chun Huang, Sin-Di Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Abdominal pain
lcsh:Diseases of the circulatory (Cardiovascular) system Cardiac & Cardiovascular Systems 030204 cardiovascular system & hematology Article 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences 0302 clinical medicine Medicine Adverse effect business.industry Adverse effects Incidence (epidemiology) Dipyridamole medicine.disease Myocardial perfusion scan lcsh:RC666-701 Anesthesia Symptom persistence Chest tightness medicine.symptom Cardiology and Cardiovascular Medicine business Myocardial perfusion scans medicine.drug |
| Zdroj: | International Journal of Cardiology: Heart & Vasculature, Vol 14, Iss C, Pp 14-19 (2017) International Journal of Cardiology. Heart & Vasculature Scipedia Open Access Scipedia SL |
| ISSN: | 2352-9067 |
| Popis: | Aim and Background Dipyridamole-induced stress myocardial perfusion scans (MPS) has been widely used for management of coronary artery disease. The adverse effects of dipyridamole and other stress agents have been evaluated. The aim of this research is to confirm the dynamic data on dipyridamole side effects during MPS. Methods We collected data of 183 patients who underwent dipyridamole-induced stress MPS by retrospectively reviewing their clinical records, which included the severity of dipyridamole side effects in 3 min, 10 min, and 20 min after infusion. The incidence and severity at all three points, including the effect of age and gender, were obtained. Results Adverse effects occurred in 96 patients (69.6%). The most frequent symptoms were dizziness (42.8%), chest tightness (24.6%), abdominal pain (18.1%), and headache (15.2%). Most symptoms were Grade 1 to 2, according to the grading system for common terminology criteria. The median duration of symptom persistence was 36 min, not significantly different among age and gender. Conclusion This study demonstrates that the adverse effects of dipyridamole were generally minimal and its duration was acceptable for clinical usage. |
| Databáze: | OpenAIRE |
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