Fragility of the esophageal mucosa: A pathognomonic endoscopic sign of primary eosinophilic esophagitis?
| Autor: | Alex Straumann, Pius Heer, Hans-Uwe Simon, Hans-Peter Spichtin, Livio Rossi, Christoph Beglinger |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Asymptomatic Gastroenterology Esophagus Pathognomonic Internal medicine Eosinophilia medicine Esophagitis Humans Radiology Nuclear Medicine and imaging Eosinophilic esophagitis Mucous Membrane medicine.diagnostic_test business.industry Esophageal disease Middle Aged medicine.disease Dilatation Dysphagia Endoscopy medicine.anatomical_structure Esophagoscopy medicine.symptom Deglutition Disorders business |
| Zdroj: | Gastrointestinal Endoscopy. 57:407-412 |
| ISSN: | 0016-5107 |
| DOI: | 10.1067/mge.2003.123 |
| Popis: | Background: Primary eosinophilic esophagitis, a chronic inflammatory disorder of the esophagus, evokes recurrent dysphagia. Endoscopy is often unremarkable, and no consensus exists regarding management of resultant dysphagia. The response of a series of patients with primary eosinophilic esophagitis to dilation is reported together with a description of a possibly pathognomonic sign: fragile esophageal mucosa, for which the term "crepe-paper" mucosa is introduced. Methods: Five men underwent endoscopy because of dysphagia confirmed (clinically, endoscopically, and histologically) to be caused by primary eosinophilic esophagitis and were treated by bouginage. Observations: All patients had extremely fragile, inelastic, and delicate mucosa, which tore easily even with minor trauma. After the procedure, patients remained asymptomatic for 3 to 24 months. Conclusions: Primary eosinophilic esophagitis is characterized by fragile esophageal mucosa that readily tears in response to minor trauma during otherwise uneventful diagnostic endoscopy. This "crepe-paper" sign may alert endoscopists to the presence of the disease when other mucosal alterations are lacking. Dilation is effective for patients with symptoms with minimal morbidity, despite development of disquieting lesions in response to the procedure. |
| Databáze: | OpenAIRE |
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