Nonenhanced ECG-gated quiescent-interval single-shot MRA (QISS-MRA) of the lower extremities: Comparison with contrast-enhanced MRA
| Autor: | Peter Schmitt, Malte Kelm, Dirk Blondin, Hans-Jörg Wittsack, Rotem S. Lanzman, J Klasen, Falk Miese, Michael Quentin, Christian Heiss, Xiaoming Bi, J. Kuhlemann, Roberto Sansone, Gerald Antoch, Patric Kröpil |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Image quality media_common.quotation_subject Contrast Media Constriction Pathologic Sensitivity and Specificity Magnetic resonance angiography Constriction Electrocardiography Peripheral Arterial Disease medicine.artery medicine Humans Contrast (vision) Radiology Nuclear Medicine and imaging cardiovascular diseases Aged media_common Aorta medicine.diagnostic_test business.industry Single shot Reproducibility of Results General Medicine Middle Aged medicine.disease eye diseases nervous system diseases Stenosis Lower Extremity cardiovascular system Female Radiology business Magnetic Resonance Angiography circulatory and respiratory physiology |
| Zdroj: | Clinical Radiology. 67:441-446 |
| ISSN: | 0009-9260 |
| Popis: | Aim To evaluate electrocardiogram (ECG)-gated quiescent-interval single-shot magnetic resonance angiography (QISS-MRA) for nonenhanced assessment of peripheral artery occlusive disease (PAOD) using contrast-enhanced MRA (CE-MRA) as the reference standard. Materials and methods Twenty-seven patients (mean age 66.6 ± 10.8 years) with PAOD were included in the study. QISS-MRA and CE-MRA of the lower extremity were performed using a 1.5 T MR scanner. In each patient, subjective image quality and the degree of stenosis were evaluated on a four-point scale for 15 predefined arterial segments. Results Twenty-five of the 27 patients were considered for analysis. Subjective image quality of QISS-MRA was significantly lower for the distal aorta, pelvic arteries, and femoral arteries as compared to CE-MRA (p < 0.01), while no significant difference was found for other vascular segments. The degree of stenosis was overestimated with QISS-MRA in 23 of 365 (6.3%) segments and underestimated in two of 365 (0.5%) segments. As compared to CE-MRA, QISS-MRA had a high sensitivity (98.6%), specificity (96%) as well as positive and negative predictive value (88.7 and 99.6%, respectively) for the detection of significant stenosis (≥50%). Conclusion ECG-gated QISS-MRA is a promising imaging technique for reliable assessment of PAOD without the use of contrast material. |
| Databáze: | OpenAIRE |
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