| Autor: |
I. Casetta, P. Contri, R. Marconi, P. Vanni, G. Moro, G. Coppola, M. Onofri, G. C. Comi, G. Finali, G P Nordera, G. Bino, E. Paolino, G. D'Asta, R. Sterzi, C. Chiaro, C. Scoppetta, Giorgio Giuliani, S. Meregalli, M. Piccirilli, M. Comola, Claudio Pacchetti, A. Peppe, E. Cossutta, G. Scigliano, P. Bassi, A. Agnoli, S. Gangemi, E. Fincati, Paolo Stanzione, G. Lovicu, Francesca Rossi, R. Massetani, I. Currado, G. Tomelleri, M. De Mari, Paolo Lamberti, E. Nardelli, Francesco Carella, M. Ferrarini, S. Genitrini, P. Caffarra, M. Pederzoli, G. Campanella, P. Piola, Massimo Musicco, A. Angeleri, R. Huber, F. Iemolo, Anna Rita Bentivoglio, Tommaso Caraceni, G. Trianni, G. L. Lenzi, P. Achille, Ettore Beghi, Antonella Castellano, Alessandra Solari, A. Franciosi, P. Marini, M. Gasparini, R. Freschi, S. Bandinelli, L. Curatola, Alberto Albanese, Emilia Martignoni, A. Nicolosi, F. Salsa, R. Galli, Giuseppe Nappi, P. Scaglioni, G. De Michele, R. Semprini, A. Lorizio, L. Capus, G. Giminiani |
| Jazyk: |
angličtina |
| Rok vydání: |
1992 |
| Předmět: |
|
| Popis: |
On the long term Parkinson Disease (PD) treatment is often complicated by the occurrence of motor fluctuations. To find out whether early treatment of PD with levodopa, dopaminoagonists or 1-deprenyl is associated with any difference in motor fluctuations occurrence, the Italian Parkinson Study Groups initiated a multicenter, randomized study. Since November 1988, 475 patients cequiring effective treatment for idiopathic PD have been randomized to receive levodopa, dopoamine agonists or deprenyl. After 2 months of therapy, all patients evaluated with the Unified Parkinson Disease Rating Scale showed a significant amelioration. Daily living activities were more impaired in patients treated with deprenyl. Study design is presented and first resuts are discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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