The suppression effects of feeding and mechanisms in CRF system of animals
| Autor: | Ni Tang, Bin Wang, Mei Wang, Hu Chen, Shuyao Wang, Xin Zhang, Jinwen Qi, Zhiqiong Li, Defang Chen, Ya Li, Shaoqi Xu, Bo Zhou |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
endocrine system medicine.medical_specialty Sauvagine Corticotropin-Releasing Hormone Peptide Hormones Urotensins Appetite Biology Amphibian Proteins 03 medical and health sciences 0302 clinical medicine Internal medicine Genetics Homologous chromosome medicine Animals Receptor Gene Urocortins Urocortin Gastrointestinal tract Mechanism (biology) Binding protein Brain General Medicine Feeding Behavior 030104 developmental biology Endocrinology 030220 oncology & carcinogenesis Carrier Proteins hormones hormone substitutes and hormone antagonists |
| Zdroj: | Gene. 733 |
| ISSN: | 1879-0038 |
| Popis: | CRF system is comprised of 4 homologous lineages, 2 main receptors (CRF-R1 and CRF-R2), and a binding protein CRF-BP. The homologous lineages are corticotropin-releasing factor (CRF), urotensin I (UI)/sauvagine (SVG)/urocortin 1 (UCN1), urocortin 2 (UCN2), and urocortin 3 (UCN3), and UI, SVG, UCN1 are orthologous genes. CRF system genes are widely distributed in the brain and gastrointestinal tract, which may relate to feeding regulation. According the research progress about CRF system on mammals and non-mammals, this paper summarized the discovery, structure, tissue distribution, appetite regulation and mechanism of CRF system in animals, which can provide the reference for further research and production of feeding regulation and growth in mammals and fish species. |
| Databáze: | OpenAIRE |
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