Uncontrolled asthma and recurring pulmonary opacities:just asthma?

Autor: Poul Henning Madsen, Christian B. Laursen, Jesper Rømhild Davidsen
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Glucocorticoids/therapeutic use
medicine.medical_specialty
Antifungal Agents
Delayed Diagnosis
Prednisolone
Prednisolone/therapeutic use
Immunoglobulin E
Asthma/diagnosis
Article
Lung/diagnostic imaging
Diagnosis
Differential
medicine
Eosinophilia
Humans
Intensive care medicine
Glucocorticoids
Lung
Asthma
Bronchiectasis
biology
business.industry
Aspergillus fumigatus
Aspergillosis
Allergic Bronchopulmonary
Pneumonia
General Medicine
Middle Aged
medicine.disease
Dermatology
respiratory tract diseases
medicine.anatomical_structure
Pneumonia/diagnosis
biology.protein
Aspergillosis
Allergic Bronchopulmonary/diagnosis
Itraconazole/therapeutic use
Immunoglobulin E/immunology
Antifungal Agents/therapeutic use
Aspergillus fumigatus/immunology
Female
Itraconazole
Allergic bronchopulmonary aspergillosis
medicine.symptom
business
Tomography
X-Ray Computed
medicine.drug
Zdroj: Rømhild Davidsen, J, Madsen, P H & Laursen, C B 2014, ' Uncontrolled asthma and recurring pulmonary opacities : just asthma? ', B M J Case Reports . https://doi.org/10.1136/bcr-2013-202428
DOI: 10.1136/bcr-2013-202428
Popis: In asthma, when comorbidities and common causes of poor control have been considered and treated, the clinician may speculate, 'Is it all asthma?'. In patients with uncontrolled atopic asthma with recurring episodes of symptoms mimicking pneumonia, the suspicion of allergic bronchopulmonary aspergillosis (ABPA) should remain high. ABPA is caused by a complex immunological hypersensitivity reaction to colonisation with Aspergillus fumigatus in the bronchial tree, and is characterised by the presence of atopic asthma, blood eosinophilia, migrating pulmonary opacities and potential bronchiectasis. This case report describes a delay in diagnosing ABPA which was imitating pneumonia. The clinician should pay increased attention to ABPA and test for this in patients with uncontrolled asthma with an ongoing requirement for oral corticosteroids and/or antibiotics and with pulmonary opacities on chest imaging.
Databáze: OpenAIRE
Externí odkaz: