Some Unusual Considerations about Vessel Walls and Wall Stresses
| Autor: | Pierre-André Doriot |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Statistics and Probability
Repair processes Materials science General Immunology and Microbiology Atmospheric pressure Applied Mathematics Vacuum pressure Models Cardiovascular Blood Pressure General Medicine Mechanics General Biochemistry Genetics and Molecular Biology Compressive strength Transmural pressure Modeling and Simulation Cardiac hypertrophy Ultimate tensile strength Blood Vessels Humans Cylinder stress Stress Mechanical General Agricultural and Biological Sciences |
| Zdroj: | Journal of Theoretical Biology. 221:133-141 |
| ISSN: | 0022-5193 |
| DOI: | 10.1006/jtbi.2003.3182 |
| Popis: | The "zero-stress state" of blood vessels is usually defined with respect to the atmospheric pressure p(a) ( approximately 750 mmHg). As a consequence, circumferential and axial wall stresses due to a positive transmural pressure can only be positive and thus, by definition, only tensile. If the zero-stress state were defined with respect to vacuum pressure (0 mmHg), the compressive stress -p(a) generated by p(a) everywhere in the wall would, however, be included so that negative (=compressive) wall stresses would formally become possible. In order to examine the consequences this alternative definition would have for arteries, we have compared radial, circumferential, and axial stresses calculated "conventionally" to the values they take when the zero-stress state is defined "correctly" by reference to the vacuum pressure. It turns out that, under normal physiologic conditions, axial stress and perhaps also circumferential stress might well be compressive in many elastic and conductance arteries, contrary to the intuitive conviction of many people. Since the type of stresses a vessel wall is submitted to may be highly relevant for its structure and mechanical properties, this unconventional way of considering wall stresses may reveal unsuspected relationships between wall stresses on one side, and wall structure, vessel growth, adaptation and repair processes, atherosclerosis, angioplasty or stenting on the other side. Similar considerations might also prove useful with regard to cardiac hypertrophy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect