Positive Selection and Gene Expression Analyses from Salivary Glands Reveal Discrete Adaptations within the Ecologically Diverse Bat Family Phyllostomidae
| Autor: | Michael W. Vandewege, Caleb D. Phillips, Cibele G. Sotero-Caio |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
AcademicSubjects/SCI01140 Submandibular Gland Adaptation Biological selection 010603 evolutionary biology 01 natural sciences Transcriptome 03 medical and health sciences Molecular evolution Chiroptera Genetics medicine submandibular glands Animals Selection Genetic Gene Ecology Evolution Behavior and Systematics Selection (genetic algorithm) 030304 developmental biology 0303 health sciences biology Salivary gland molecular evolution AcademicSubjects/SCI01130 Feeding Behavior biology.organism_classification Biological Evolution Submandibular gland immunity Diet medicine.anatomical_structure Vampire bat Evolutionary biology Adaptation Research Article |
| Zdroj: | Genome Biology and Evolution |
| ISSN: | 1759-6653 |
| Popis: | The leaf-nosed bats (Phyllostomidae) are outliers among chiropterans with respect to the unusually high diversity of dietary strategies within the family. Salivary glands, owing to their functions and high ultrastructural variability among lineages, are proposed to have played an important role during the phyllostomid radiation. To identify genes underlying salivary gland functional diversification, we sequenced submandibular gland transcriptomes from phyllostomid species representative of divergent dietary strategies. From the assembled transcriptomes, we performed an array of selection tests and gene expression analyses to identify signatures of adaptation. Overall, we identified an enrichment of immunity-related gene ontology terms among 53 genes evolving under positive selection. Lineage-specific selection tests revealed several endomembrane system genes under selection in the vampire bat. Many genes that respond to insulin were under selection and differentially expressed genes pointed to modifications of amino acid synthesis pathways in plant-visitors. Results indicate salivary glands have diversified in various ways across a functional diverse clade of mammals in response to niche specializations. |
| Databáze: | OpenAIRE |
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