Generation of an artificial human B cell line test system using Transpo-mAbTM technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins

Autor: Mira Woitok, Rainer Fischer, Judith Niesen, Ulf Grawunder, Thomas Nachreiner, Roger R. Beerli, Stefan Barth, Rolf Fendel, Diana Klose
Přispěvatelé: Publica
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
B Cells
Cell Lines
lcsh:Medicine
Apoptosis
Toxicology
Pathology and Laboratory Medicine
Biochemistry
Granzymes
Immunoglobulin G
Cell Fusion
White Blood Cells
Spectrum Analysis Techniques
Animal Cells
Immunotoxin
Medicine and Health Sciences
Tetanus Toxoid
Cytotoxic T cell
lcsh:Science
Cell Engineering
Cell Analysis
Fluorescence-Activated Cell Sorting
B-Lymphocytes
Cytotoxicity Assay
Multidisciplinary
Cell fusion
Cell Death
biology
Chemistry
Immunotoxins
Recombinant Proteins
Cell biology
Bioassays and Physiological Analysis
Cell Processes
Spectrophotometry
Biological Cultures
Cytophotometry
ddc:500
Cellular Types
Research Article
Cell Physiology
Cell Viability Testing
Immune Cells
Recombinant Fusion Proteins
Immunology
B-cell receptor
Receptors
Antigen
B-Cell
Research and Analysis Methods
03 medical and health sciences
Cell Line
Tumor
Humans
Antibody-Producing Cells
Blood Cells
Hybridomas
business.industry
lcsh:R
Biology and Life Sciences
Proteins
Cell Biology
Fusion protein
Biotechnology
Granzyme B
030104 developmental biology
Granzyme
biology.protein
lcsh:Q
business
Single-Chain Antibodies
Zdroj: PLOS ONE 12(7), e0180305 (2017). doi:10.1371/journal.pone.0180305
PLoS ONE, Vol 12, Iss 7, p e0180305 (2017)
PLoS ONE
DOI: 10.18154/rwth-2017-07408
Popis: PLoS one 12(7), e0180305 (2017). doi:10.1371/journal.pone.0180305
Published by PLoS, Lawrence, Kan.
Databáze: OpenAIRE
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