Immunosensing by a Synthetic Ligand-Gated Ion Channel
Autor: | Horst Vogel, Remo Guerrini, Wolf-Peter Ulrich, Samuel Terrettaz, Antonio Silvio Verdini |
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Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Angewandte Chemie International Edition. 40:1740-1743 |
ISSN: | 1521-3773 1433-7851 |
Popis: | Gating of an artificial receptor was monitored for the first time by impedance spectroscopy in tethered lipid bilayer. Subnanomolar concns. of antibody were detected by modulation of the channel activity. The principle of gating by an antibody is particularly attractive because of its general character, and thus opens new possibility of immunosensing. [on SciFinder (R)] |
Databáze: | OpenAIRE |
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