Immunosensing by a Synthetic Ligand-Gated Ion Channel

Autor:	Horst Vogel, Remo Guerrini, Wolf-Peter Ulrich, Samuel Terrettaz, Antonio Silvio Verdini
Rok vydání:	2001
Předmět:	chemistry.chemical_classification chemistry Analytical chemistry Biophysics Ligand-gated ion channel Peptide General Medicine General Chemistry Gating Antibodies Impedance spectroscopy Lipid bilayers Peptides Receptors Lipid bilayer Catalysis Dielectric spectroscopy
Zdroj:	Angewandte Chemie International Edition. 40:1740-1743
ISSN:	1521-3773 1433-7851
Popis:	Gating of an artificial receptor was monitored for the first time by impedance spectroscopy in tethered lipid bilayer. Subnanomolar concns. of antibody were detected by modulation of the channel activity. The principle of gating by an antibody is particularly attractive because of its general character, and thus opens new possibility of immunosensing. [on SciFinder (R)]
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2673103d77583124938efc855d97de52 https://doi.org/10.1002/1521-3773(20010504)40:9<1740::aid-anie17400>3.0.co Zobrazit plný text záznamu Plný text