Electroencephalographic features of benign adult familial myoclonic epilepsy
| Autor: | Sadatoshi Tsuji, Tomoko Toyota, Akihiro Tanaka, Naoki Akamatsu, Takenori Uozumi |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Benign adult familial myoclonic epilepsy Pediatrics medicine.medical_specialty Epilepsies Myoclonic Electroencephalography Epilepsy Seizures Physiology (medical) Hyperventilation medicine Humans In patient Aged Aged 80 and over Cerebral Cortex medicine.diagnostic_test Significant difference Middle Aged medicine.disease Sensory Systems Neurology Anesthesia Referral center Female Neurology (clinical) medicine.symptom Psychology Myoclonus |
| Zdroj: | Clinical Neurophysiology. 125:250-254 |
| ISSN: | 1388-2457 |
| Popis: | Objective To investigate electroencephalographic (EEG) features of benign adult familial myoclonic epilepsy (BAFME). Methods We reviewed interictal EEG features in patients with BAFME treated between April 2005 and November 2012 at a tertiary referral center. The diagnostic criteria for BAFME were the presence of infrequent generalized tonic–clonic seizures, myoclonus or myoclonic seizures, and autosomal dominant inheritance. Interictal EEG findings of epilepsy with generalized tonic–clonic seizure only (EGTCS) were reviewed for comparison. We randomly selected 10 generalized spike/polyspike and wave complexes (GSW) for each BAFME patient and measured the duration of them. Photic stimulation and hyperventilation were performed in all. Results Nineteen (eight men, 11 women) patients with BAFME were included in this study. The mean frequency of GSW was 4.3 ± 1.0 Hz (mean ± SD, n = 14) in BAFME and 3.2 ± 0.8 Hz ( n = 10) in EGTCS. There was a statistically significant difference ( p = 0.008) between the two. Photoparoxysmal responses (PPR) were noted in 18 (95%) patients with BAFME but 1 (10%) with EGTCS. Conclusion Faster frequency of GSW, compared with that in EGTCS, accompanied by PPR may be characteristic EEG features of BAFME. Significance These findings may lead the diagnosis of BAFME. |
| Databáze: | OpenAIRE |
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