Compliance with pregnancy prevention measures during isotretinoin therapy
| Autor: | Eleanor Bimla Schwarz, James Swan, Laura K. Ferris, Jacqueline F. Moreau, Mary-Katharine Collins, Matthew Hastings, Dan Opel, Noel Prevost |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
medicine.medical_specialty Oral contraceptive pill media_common.quotation_subject Population Dermatology Intrauterine device Medication Adherence Condoms Young Adult Pregnancy Acne Vulgaris medicine Humans Isotretinoin education Contraception Behavior Sexual Abstinence media_common Gynecology education.field_of_study Obstetrics business.industry Abnormalities Drug-Induced Abstinence United States Contraception Family planning Pill Female business Developed country Contraceptives Oral medicine.drug |
| Zdroj: | Journal of the American Academy of Dermatology. 70:55-59 |
| ISSN: | 0190-9622 |
| Popis: | Background Approximately 150 women annually become pregnant while taking isotretinoin despite participation in the iPLEDGE program. Noncompliance with the requirement to be abstinent or use 2 contraceptive methods may be a contributing factor. Objective We sought to determine the degree of adherence to contraception or abstinence among women taking isotretinoin. Methods We conducted an anonymous survey of women of childbearing potential taking isotretinoin for at least 2 months. Results Among 75 participants, 21 (28%) chose abstinence as their primary means of pregnancy prevention, of whom 4 (19%) were sexually active during treatment. The most commonly chosen contraceptive methods among the 39 women who were sexually active were condoms (35, 90%) and oral contraceptive pills (18, 46%). Twelve women (31%) admitted to having intercourse at least once using 1 or fewer forms of contraception; 10 failed to use condoms, and 1 reported completely unprotected intercourse. Among sexually active oral contraceptive pill users, 7 (39%) reported missing 1 or more pills in the previous month. Limitations Data were self-reported, thus participants may have inaccurately reported contraception use. Conclusions Encouraging the use of highly effective, patient-independent contraception and limiting abstinence to women who have never been sexually active may further reduce the rate of isotretinoin-exposed pregnancies. |
| Databáze: | OpenAIRE |
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