Factors associating with differences in the incidence of renal replacement therapy among elderly: Data from the ERA-EDTA Registry
| Autor: | Ziad A. Massy, Gabriel de Arriba, Cécile Couchoud, Visnja Lezaic, James G. Heaf, Ülle Pechter, Marie Evans, Kitty J Jager, Johan De Meester, Jaakko Helve, Carola Grönhagen-Riska, Halima Resić, Rafael Santamaria, Jose M. Abad-Díez, Runolfur Palsson, Anneke Kramer, Oscar Zurriaga, Patrik Finne, Carmen Santiuste de Pablos, Maurizio Nordio, Florence Glaudet |
|---|---|
| Přispěvatelé: | ACS - Pulmonary hypertension & thrombosis, APH - Aging & Later Life, Medical Informatics, APH - Quality of Care, APH - Methodology, APH - Global Health, Department of Medicine, Nefrologian yksikkö, Clinicum, University of Helsinki, Faculty of Medicine, HUS Abdominal Center |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
CHRONIC KIDNEY-DISEASE
Male medicine.medical_treatment 030232 urology & nephrology DECISION-MAKING 030204 cardiovascular system & hematology urologic and male genital diseases INITIATION 0302 clinical medicine QUALITY-OF-LIFE DIALYSIS education.field_of_study Data Collection Incidence Incidence (epidemiology) Age Factors Middle Aged female genital diseases and pregnancy complications 3. Good health Europe Renal Replacement Therapy Survival Rate Nephrology Female Hemodialysis Adult Population elderly FLANDERS EXPLORATION 03 medical and health sciences COMPARATIVE SURVIVAL medicine Humans Renal replacement therapy ESRD education Aged Transplantation OLDER PATIENTS Proportional hazards model business.industry 3126 Surgery anesthesiology intensive care radiology medicine.disease Comorbidity Confidence interval 3121 General medicine internal medicine and other clinical medicine Relative risk Kidney Failure Chronic business CONSERVATIVE MANAGEMENT Demography |
| Zdroj: | Nephrology, dialysis, transplantation, 33(8), 1428-1435. Oxford University Press |
| ISSN: | 0931-0509 |
| Popis: | Background. The incidence of renal replacement therapy (RRT) in the general population >= 75 years of age varies considerably between countries and regions in Europe. Our aim was to study characteristics and survival of elderly RRT patients and to find explanations for differences in RRT incidence. Methods. Patients >= 75 years of age at the onset of RRT in 2010-2013 from 29 national or regional registries providing data to the European Renal Association-European Dialysis and Transplant Association Registry were included. Chi-square and Mann-Whitney U tests were used to assess variation in patient characteristics and linear regression was used to study the association between RRT incidence and various factors. Kaplan-Meier curves and Cox regression were employed for survival analyses. Results. The mean annual incidence of RRT in the age group >= 75 years of age ranged from 157 to 924 per million age-related population. The median age at the start of RRT was higher and comorbidities were less common in areas with higher RRT incidence, but overall the association between patient characteristics and RRT incidence was weak. The unadjusted survival was lower in high-incidence areas due to an older age at onset of RRT, but the adjusted survival was similar [relative risk 1.00 (95% confidence interval, 0.97-1.03)] in patients from low- and high-incidence areas. Conclusions. Variation in the incidence of RRT among the elderly across European countries and regions is remarkable and could not be explained by the available data. However, the survival of patients in low-and high-incidence areas was remarkably similar. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|