Magnesium Sulfate Combined with a Levobupivacaine Periarticular Cocktail for Analgesia in the Early Postoperative Period after Total Knee Arthroplasty
| Autor: | Hao Peng, Hang Wu, Zhenrui Zhao, Hengzhong Liu, Xiaozhou Zhang, Wei Li |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Analgesic effect
Visual analogue scale medicine.medical_treatment Total knee arthroplasty chemistry.chemical_element Knee Joint Injections Intra-Articular 03 medical and health sciences Magnesium Sulfate 0302 clinical medicine Medicine Humans Orthopedics and Sports Medicine Postoperative Period Anesthetics Local Leg elevation Arthroplasty Replacement Knee Saline Levobupivacaine 030222 orthopedics Pain Postoperative business.industry Magnesium 030229 sport sciences chemistry Anesthesia Surgery Analgesia business medicine.drug |
| Zdroj: | The journal of knee surgery. 34(13) |
| ISSN: | 1938-2480 |
| Popis: | This study aimed to evaluate the analgesic effect of magnesium sulfate combined with a levobupivacaine periarticular cocktail in the early postoperative period after total knee arthroplasty (TKA). A total of 60 patients who underwent primary unilateral TKA in our department from March 2018 to May 2019 were prospectively selected and randomly divided into the trial group (30 patients with 20 mL of magnesium sulfate 250 mg + levobupivacaine 50 mg + triamcinolone 25 mg + 0.9% normal saline) and the control group (30 patients with 20 mL of levobupivacaine 50 mg + triamcinolone 25 mg + 0.9% normal saline). Visual analog scale (VAS) scores at 6, 12, 24, 48, and 72 hours postoperatively during rest; VAS scores at 12, 24, 48, and 72 hours postoperatively during motion; the time required to reach 30 degrees straight leg elevation and 60 degrees active knee flexion; and the analgesia pump dosage at 6, 12, 24, and 48 hours postoperatively were recorded. Magnesium sulfate combined with levobupivacaine injection around the knee joint can significantly prolong the time of postoperative analgesia, significantly reduce the use of postoperative analgesics, and effectively alleviate early postoperative pain after TKA. |
| Databáze: | OpenAIRE |
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