Multidimensional evaluation of voice outcomes following total laryngectomy: a prospective multicenter cohort study
Autor: | Kelly Jones, Daniel Novakovic, Lydia Natsis, Danielle B. Stone, Rob J.J.H. van Son, Emma Charters, Klaske E. van Sluis, Michiel W. M. van den Brekel, Lisette van der Molen, Carsten E. Palme, Anthony John MCGuinness, Richard Dirven |
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Přispěvatelé: | Oral and Maxillofacial Surgery, ACLC (FGw), AIHR (FGw), MKA AMC (OII, ACTA), Maxillofacial Surgery (AMC) |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Linear mixed effect model
medicine.medical_specialty Coping (psychology) SDG 16 - Peace medicine.medical_treatment Patient-reported Total laryngectomy Laryngectomy Speech Acoustics 03 medical and health sciences Perceptual 0302 clinical medicine Speech Production Measurement Statistical significance medicine Communication methods Humans Prospective Studies 030223 otorhinolaryngology Netherlands Descriptive statistics business.industry SDG 16 - Peace Justice and Strong Institutions Australia General Medicine Acoustics Dysphonia Justice and Strong Institutions Otorhinolaryngology 030220 oncology & carcinogenesis Voice outcome Physical therapy business Head and Neck Cohort study |
Zdroj: | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS), 278(4), 1209-1222. Springer Verlag European Archives of Oto-Rhino-Laryngology, 278(4). Springer Verlag van Sluis, K E, van Son, R J J H, van der Molen, L, MCGuinness, A J, Palme, C E, Novakovic, D, Stone, D, Natsis, L, Charters, E, Jones, K, Dirven, R & van den Brekel, M W M 2021, ' Multidimensional evaluation of voice outcomes following total laryngectomy: a prospective multicenter cohort study ', European Archives of Oto-Rhino-Laryngology, vol. 278, no. 4, pp. 1209–1222 . https://doi.org/10.1007/s00405-020-06216-z European Archives of Oto-Rhino-Laryngology |
ISSN: | 0937-4477 |
Popis: | Purpose The purpose of this study is to assess the general course of acoustic, patient rated, and clinician-rated voice outcomes from pre- up to 12 months post total laryngectomy. Methods Patients admitted to a total laryngectomy in five participating hospitals in Australia and The Netherlands were included. Assessments took place at pre-, 3 months, 6 months, and 12 months post-surgery. Voice outcomes are evaluated with the Acoustic Voice Quality Index (AVQI), perceptual scales, and patient-reported outcome measures including VHI-10 and EQ-5D-5L. Statistical analyses include descriptive statistics, t tests (pre- to 6 months post-surgery), Linear Mixed Effect models. Results The study included 43 participants. A significant worsening of AVQI is seen from pre- to post-surgery evaluated with t test (p Time as a significant factor in predicting AVQI score (p ≤ 0.001), as well as perceptual rated voice quality by the clinician (p = 0.015) and patient-reported perceptual rated voice quality (p = 0.002). No statistical significance was found in VHI-10 scores over time. Conclusion Successful TE-speech was achieved in most participants, some had to rely on augmentative alternative communication methods. Patient-reported outcomes indicate acceptance of the condition and sufficient coping in the long term. However, acoustic rated voice quality is abnormal at all post-surgery time-points. AVQI proved to be a useful instrument to evaluate TE-speech. There is a need for validation and determination of cut-off values for VHI-10 and AVQI for use in TE-speech. |
Databáze: | OpenAIRE |
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