Multidimensional evaluation of voice outcomes following total laryngectomy: a prospective multicenter cohort study

Autor: Kelly Jones, Daniel Novakovic, Lydia Natsis, Danielle B. Stone, Rob J.J.H. van Son, Emma Charters, Klaske E. van Sluis, Michiel W. M. van den Brekel, Lisette van der Molen, Carsten E. Palme, Anthony John MCGuinness, Richard Dirven
Přispěvatelé: Oral and Maxillofacial Surgery, ACLC (FGw), AIHR (FGw), MKA AMC (OII, ACTA), Maxillofacial Surgery (AMC)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS), 278(4), 1209-1222. Springer Verlag
European Archives of Oto-Rhino-Laryngology, 278(4). Springer Verlag
van Sluis, K E, van Son, R J J H, van der Molen, L, MCGuinness, A J, Palme, C E, Novakovic, D, Stone, D, Natsis, L, Charters, E, Jones, K, Dirven, R & van den Brekel, M W M 2021, ' Multidimensional evaluation of voice outcomes following total laryngectomy: a prospective multicenter cohort study ', European Archives of Oto-Rhino-Laryngology, vol. 278, no. 4, pp. 1209–1222 . https://doi.org/10.1007/s00405-020-06216-z
European Archives of Oto-Rhino-Laryngology
ISSN: 0937-4477
Popis: Purpose The purpose of this study is to assess the general course of acoustic, patient rated, and clinician-rated voice outcomes from pre- up to 12 months post total laryngectomy. Methods Patients admitted to a total laryngectomy in five participating hospitals in Australia and The Netherlands were included. Assessments took place at pre-, 3 months, 6 months, and 12 months post-surgery. Voice outcomes are evaluated with the Acoustic Voice Quality Index (AVQI), perceptual scales, and patient-reported outcome measures including VHI-10 and EQ-5D-5L. Statistical analyses include descriptive statistics, t tests (pre- to 6 months post-surgery), Linear Mixed Effect models. Results The study included 43 participants. A significant worsening of AVQI is seen from pre- to post-surgery evaluated with t test (p Time as a significant factor in predicting AVQI score (p ≤ 0.001), as well as perceptual rated voice quality by the clinician (p = 0.015) and patient-reported perceptual rated voice quality (p = 0.002). No statistical significance was found in VHI-10 scores over time. Conclusion Successful TE-speech was achieved in most participants, some had to rely on augmentative alternative communication methods. Patient-reported outcomes indicate acceptance of the condition and sufficient coping in the long term. However, acoustic rated voice quality is abnormal at all post-surgery time-points. AVQI proved to be a useful instrument to evaluate TE-speech. There is a need for validation and determination of cut-off values for VHI-10 and AVQI for use in TE-speech.
Databáze: OpenAIRE