The Biomarkers Consortium: Practice and Pitfalls of Open-Source Precompetitive Collaboration
| Autor: | M M Ennis, J Kochan, Y Chen, Maria T. Vassileva, Bret J. Musser, E C Wright, M-D Wang, Derek J. Nunez, B Schneider, John A. Wagner, S Ghosh, M Prince |
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| Rok vydání: | 2010 |
| Předmět: |
Pharmacology
Economic Competition Economic competition Knowledge management Drug Industry business.industry Bioinformatics Drug Delivery Systems Open source Drug development Drug Design Animals Humans Biomarker (medicine) Medicine Pharmacology (medical) Cooperative behavior Cooperative Behavior business Drug industry Biomarkers Randomized Controlled Trials as Topic |
| Zdroj: | Clinical Pharmacology & Therapeutics. 87:539-542 |
| ISSN: | 1532-6535 0009-9236 |
| Popis: | Precompetitive collaboration is a growing driver for innovation and increased productivity in biomedical science and drug development. The Biomarkers Consortium, a public-private platform for precompetitive collaboration specific to biomarkers, demonstrated that adiponectin has potential utility as a predictor of metabolic responses to peroxisome proliferator-activated receptor (PPAR) agonists in individuals with type 2 diabetes. Despite the challenges overcome by this project, the most important lesson learned is that cross-company precompetitive collaboration is a feasible robust approach to biomarker qualification. |
| Databáze: | OpenAIRE |
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