Three-Dimensional Volumetric Assessment of Graft Volume in Living Donor Liver Transplantation: Does It Minimise Errors of Estimation?
| Autor: | Nihar Mohapatra, Piyush Kumar Sinha, Shridhar Vasantrao Sasturkar, Viniyendra Pamecha, Kishore Gurumoorthy Subramanya Bharathy, Yashwant Patidar |
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| Rok vydání: | 2020 |
| Předmět: |
Hepatology
business.industry Liver volume medicine.medical_treatment Mean percentage error Remnant liver 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Statistical significance medicine Original Article 030211 gastroenterology & hepatology Hepatectomy Living donor liver transplantation Graft volume Vein business Nuclear medicine |
| Zdroj: | J Clin Exp Hepatol |
| ISSN: | 0973-6883 |
| Popis: | Background Accurate volumetric assessment of graft and remnant liver is essential in living donor liver transplantation (LDLT) for optimal clinical outcome in both donors and recipients. Recently, three-dimensional (3D) volumetry is proposed over conventional computed tomography (CT) volumetry to minimise errors. The aim of this study is to assess the correlation of estimated graft volume (EGV) by both the methods with actual graft weight (AGW). Methods One hundred fifty-four consecutive donors were enrolled prospectively. Conventional CT volumetry (semiautomatic) and 3D volumetry were performed using Myrian software. Total liver volume (TLV), EGV, and remnant liver volume (RLV) were assessed using both methods and correlated with intraoperatively measured AGW as the reference standard. Error of estimation was calculated accordingly. Results One hundred eighteen donors underwent right hepatectomy excluding middle hepatic vein (MHV), twenty-nine donors had left hepatectomy including MHV and six donors underwent left lateral sectionectomy. The median EGV on CT and 3D volumetry was 628.5 ml (140–1300) and 634.5 ml (156–1349), respectively. The median AGW was 647 gm (200–1004). Both CT and 3D volumetry showed strong correlation with AGW (correlation coefficients: 0.834 and 0.856, respectively). Linear correlation is as follows: (a) AGW = 99.75 + 0.818 × EGV (CT) and (b) AGW = 96.03 + 0.835 × EGV (3D). The mean percentage error for CT and 3D volumetry was 14.2 ± 12.5% and 12.2 ± 11.8%, respectively. The overall accuracy of estimation of EGV improved using 3D software (P=0.015). For the subgroup of types of graft, the difference did not reach statistical significance (P=0.062, 0.214 and 0.463 for right, left and left lateral grafts, respectively) Conclusion Both conventional CT and 3D volumetric methods strongly correlate with AGW in donors of LDLT, whereas overall accuracy of estimation of graft weight improved marginally by 3D volumetry. |
| Databáze: | OpenAIRE |
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