The footprint of recent and strong demographic decline in the genomes of Mangalitza pigs
| Autor: | Tainã Figueiredo Cardoso, Marcel Amills, Albano Beja-Pereira, István Anton, Valentin Adrian Bâlteanu, Attila Zsolnai, István Egerszegi |
|---|---|
| Přispěvatelé: | Ministerio de Economía y Competitividad (España), Ministry of Agriculture (Hungary), Ministério da Educação (Brasil), Generalitat de Catalunya, Fundaçao Capes (Brasil), Amills, Marcel [0000-0002-8999-0770], Egerszegi, I. [0000-0003-4099-9640], Zsolnai, A. [0000-0002-8382-1503], Amills, Marcel, Egerszegi, I., Zsolnai, A. |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Swine Sus scrofa Population population Admixture Breeding Biology Runs of Homozygosity Polymorphism Single Nucleotide SF1-1100 Homozygosity Animal science Animals Inbreeding structure education Demography education.field_of_study Genome Admixtures Homozygote Genetic Variation Structure Large white Genomics Breed Animal culture Domestic pig admixture Female Animal Science and Zoology homozygosity Polymorphisms polymorphisms |
| Zdroj: | Animal, Vol 13, Iss 11, Pp 2440-2446 (2019) Digital.CSIC. Repositorio Institucional del CSIC instname Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Recercat. Dipósit de la Recerca de Catalunya Recercat: Dipósit de la Recerca de Catalunya Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| ISSN: | 1751-7311 |
| Popis: | The Mangalitza pig breed has suffered strong population reductions due to competition with more productive cosmopolitan breeds. In the current work, we aimed to investigate the effects of this sustained demographic recession on the genomic diversity of Mangalitza pigs. By using the Porcine Single Nucleotid Polymorphism BeadChip, we have characterized the genome-wide diversity of 350 individuals including 45 Red Mangalitza (number of samples; n=20 from Hungary and n=25 from Romania), 37 Blond Mangalitza, 26 Swallow-belly Mangalitza, 48 Blond Mangalitza × Duroc crossbreds, 5 Bazna swine, 143 pigs from the Hampshire, Duroc, Landrace, Large White and Pietrain breeds and 46 wild boars from Romania (n=18) and Hungary (n=28). Performance of a multidimensional scaling plot showed that Landrace, Large White and Pietrain pigs clustered independently from Mangalitza pigs and Romanian and Hungarian wild boars. The number and total length of ROH (runs of homozygosity), as well as FROH coefficients (proportion of the autosomal genome covered ROH) did not show major differences between Mangalitza pigs and other wild and domestic pig populations. However, Romanian and Hungarian Red Mangalitza pigs displayed an increased frequency of very long ROH (>30 Mb) when compared with other porcine breeds. These results indicate that Red Mangalitza pigs underwent recent and strong inbreeding probably as a consequence of severe reductions in census size. Part of the research presented in this publication was funded by grant AGL2013–48742-C2–1-R awarded by the Spanish Ministry of Economy as well as by projects TKISSE and TGENRE supported by the Hungarian Ministry of Agriculture. The authors also acknowledge the support of the Spanish Ministry of Economy and Competitivity for the Center of Excellence Severo Ochoa 2016-2019 (SEV-2015-0533) grant awarded to the Centre for Research in Agricultural Genomics (CRAG). Tainã Figueiredo Cardoso was funded with a fellowship from the CAPES Foundation-Coordination of Improvement of Higher Education, Ministry of Education of the Federal Government of Brazil. Thanks also to the CERCA Programme of the Generalitat de Catalunya. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|