Assessment of the relation between initial culprit vessel patency in acute ST-elevation myocardial infarction and endothelial function
| Autor: | Jasveen J. Kandhai-Ragunath, Clemens von Birgelen, Martin G. Stoel, Carine J.M. Doggen, Bjorn de Wagenaar, Jan van Es, Frits H.A.F. de Man, Ron J.G. Peters, Harald T. Jørstad, Cees Doelman |
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| Přispěvatelé: | Amsterdam Cardiovascular Sciences, Cardiology, Amsterdam Public Health, Faculty of Behavioural, Management and Social Sciences, Health Technology & Services Research |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Endothelium medicine.medical_treatment IR-100503 Coronary Angiography Coronary artery disease Culprit Cohort Studies Electrocardiography Internal medicine Humans Medicine Vascular Patency Prospective Studies Myocardial infarction Endothelial dysfunction Prospective cohort study Aged METIS-307072 Culprit vessel patency business.industry Percutaneous coronary intervention Endothelial function Middle Aged medicine.disease ST-elevation myocardial infarction (STEMI) Reactive hyperaemia peripheral artery tonometry medicine.anatomical_structure Acute Disease Cardiology cardiovascular system Female Endothelium Vascular Cardiology and Cardiovascular Medicine business |
| Zdroj: | EuroIntervention, 10(7), 784-791. EuroPCR EuroIntervention, 10(7):137, 784-791. EuroPCR |
| ISSN: | 1774-024X |
| Popis: | Aims: To assess whether better endothelial function increases the likelihood of patients with acute ST-elevation myocardial infarction (STEMI) having initially patent culprit vessels. Clinical data on the relation between endothelial function and culprit vessel patency in STEMI patients are scarce. Methods and results: In this prospective cohort study in 71 patients with STEMI, endothelial function was non-invasively assessed by use of the reactive hyperaemia peripheral artery tonometry (RH-PAT) method at four to six weeks after the primary percutaneous coronary intervention (PPCI). The RH-PAT index measured on average 1.90±0.58. In patients with patent culprit vessels before PPCI (n=33, 46.5%), endothelial function was significantly better than in patients with occluded vessels (n=38, 53.5%) (RH-PAT index 2.08±0.34 vs. 1.75±0.35; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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