Fetal Alcohol Spectrum Disorders in a Southeastern County of the United States: Child Characteristics and Maternal Risk Traits
| Autor: | Omar A. Abdul-Rahman, Amy J. Elliott, Heather A. Mastro, Philip A. May, Dixie M. Hedrick, Wendy O. Kalberg, H. Eugene Hoyme, Barbara G. Tabachnick, Tamison Jewett, Marita Brooks, Margaret P. Adam, Julie M. Hasken, Luther K. Robinson, Julie M. Stegall, Marian A. Ortega, Melanie A. Manning, David Buckley |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Alcohol Drinking Cephalometry Fetal alcohol syndrome 030508 substance abuse Medicine (miscellaneous) Toxicology Article Executive Function 03 medical and health sciences Health problems Fetal alcohol Spatial Processing 0302 clinical medicine Memory Pregnancy Activities of Daily Living Prevalence medicine Birth Weight Humans Child Socioeconomic status Depression (differential diagnoses) Academic Success business.industry Significant difference Prenatal Care medicine.disease Southeastern United States Pregnancy Complications Affect Psychiatry and Mental health Fetal Alcohol Spectrum Disorders Case-Control Studies Maternal risk Female 0305 other medical science business 030217 neurology & neurosurgery Demography |
| Zdroj: | Alcohol Clin Exp Res |
| ISSN: | 1530-0277 0145-6008 |
| Popis: | OBJECTIVE To detail the characteristic traits of children with fetal alcohol spectrum disorders (FASDs) and maternal risk factors in a southeastern U.S. County. METHODS Independent samples were drawn from 2 different cohorts of first-grade students. All consented children (49.8%) were measured for height, weight, and head circumference, and those ≤ 25th centile entered the study along with a random sample drawn from all enrolled students. Study children were examined for physical growth, dysmorphology, and neurobehavior, and their mothers were interviewed. RESULTS Total dysmorphology scores discriminated well the physical traits of children across the FASD continuum: fetal alcohol syndrome (FAS) = 15.8, partial FAS (PFAS) = 10.8, alcohol-related neurobehavioral disorder (ARND) = 5.2, and typically developing controls = 4.4. Additionally, a neurobehavioral battery distinguished children with each FASD diagnosis from controls. Behavioral problems qualified more children for FASD diagnoses than cognitive traits. Significant proximal maternal risk variables were as follows: reports of prepregnancy drinking, drinking in any trimester, and comorbid use of other drugs in lifetime and during pregnancy, especially alcohol and marijuana (14.9% among mothers of children with FASD vs. 0.4% for controls). Distal maternal risks included reports of other health problems (e.g., depression), living unmarried with a partner during pregnancy, and a lower level of spirituality. Controlling for other drug use during pregnancy, having a child diagnosed with a FASD was 17.5 times greater for women who reported usual consumption of 3 drinks per drinking day prior to pregnancy than for nondrinking mothers (p |
| Databáze: | OpenAIRE |
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