Surgical procedures in patients with Glanzmann's thrombasthenia
| Autor: | Aby Abraham, Alok Srivastava, Punit Jain, Fouzia N. Abubacker, Anu Korula, Biju George, Vikram Mathews, Joy John Mammen, Auro Viswabandya, Abhijeet Ganapule |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Adolescent medicine.medical_treatment Factor VIIa 030204 cardiovascular system & hematology Young Adult 03 medical and health sciences 0302 clinical medicine Thrombasthenia 030202 anesthesiology hemic and lymphatic diseases Laparotomy medicine Humans In patient Child business.industry Glanzmann's thrombasthenia Thyroidectomy Hematology General Medicine Surgical procedures medicine.disease Recombinant Proteins Surgery Dental extraction Female business Major bleeding |
| Zdroj: | Blood Coagulation & Fibrinolysis. 28:171-175 |
| ISSN: | 0957-5235 |
| Popis: | Glanzmann's thrombasthenia is a rare platelet function disorder with an autosomal recessive pattern of inheritance. Achieving haemostasis in such patients who undergo surgical procedures always poses a significant challenge. Herein we report six cases of Glanzmann's thrombasthenia, who underwent nine surgeries under the cover of platelet-rich concentrates with or without recombinant activated factor VII . Of these, five were major surgeries such as thyroidectomy, laparotomy, Hartmann's procedure, reversal of Hartmann's procedure and a complete dental extraction. All five procedures were successfully done without any major bleeding. The major cost incurred in these procedures is due to the large number of blood products used and recombinant activated factor VII if used. |
| Databáze: | OpenAIRE |
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