Role of Proteolytic Enzyme Inhibitors on Carious and Eroded Dentin Associated With a Universal Bonding System
| Autor: | Larissa Pinceli Chaves, Cristina de Mattos Pimenta Vidal, Polliana Mendes Candia Scaffa, Linda Wang, Heitor Marques Honório, Leo Tjäderhane, T. N. Machado, M. C. Giacomini |
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| Rok vydání: | 2017 |
| Předmět: |
Dental Stress Analysis
Materials science CLOREXIDINA Dentistry Carious Dentin Dental Cements 02 engineering and technology Dental bonding Dental Caries In Vitro Techniques Composite Resins 03 medical and health sciences 0302 clinical medicine stomatognathic system Tensile Strength Adhesive system Ultimate tensile strength Dentin medicine Humans Protease Inhibitors Tooth Erosion Composite material General Dentistry business.industry Bond strength Proteolytic enzymes Dental Bonding 030206 dentistry 021001 nanoscience & nanotechnology medicine.anatomical_structure 0210 nano-technology business |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 1559-2863 |
| Popis: | SUMMARY Objectives: The aim of this study was to evaluate the effect of proteolytic inhibitors on the bond strength of a universal adhesive system (etch-and-rinse mode) applied to artificial carious and eroded dentin. Methods: Ninety molars were prepared and randomly divided into three groups according to the substrate: N, no challenges; ACD, artificial carious dentin simulation and ERO, artificial erosion simulation with orange juice. All groups were redivided into three subgroups according to the dentin pretreatment: W, water; CHX, 2% digluconate chlorhexidine; and E-64 (trans-epoxysuccinyl-L-leucylamido-[4-guanidino] butane), 5 μM E-64 inhibitor. They constituted a total of nine groups (n=10): N-W, N-CHX, N-E64, ACD-W, ACD-CHX, ACD-E64, ERO-W, ERO-CHX, and ERO-E64. All specimens were restored with Adper Single Bond Universal/Filtek Z250. Beams (0.64 mm2) were obtained and subjected to the microtensile test (μTBS) in a universal testing machine at 0.5 mm/min. The failure mode of the interfaces was determined by optical microscopy (40× magnification). Data were statistically analyzed by three-way analysis of variance and Tukey tests (p |
| Databáze: | OpenAIRE |
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