Immunosuppression as a factor in allowing mucosal disease to occur
| Autor: | Maura Ferrari, G Castrucci, F. Frigeri, V. Traldi |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
viruses
medicine.medical_treatment Immunology Antibodies Viral Microbiology Virus Dexamethasone Pathogenesis Species Specificity medicine Immunology and Allergy Animals Immunosuppression Therapy Chemotherapy Diarrhea Viruses Bovine Viral General Veterinary biology fungi Pestivirus Immunosuppression General Medicine biology.organism_classification Virology Infectious Diseases Togaviridae Bovine Virus Diarrhea-Mucosal Disease Cattle Viral disease medicine.drug |
| Zdroj: | Comparative immunology, microbiology and infectious diseases. 17(2) |
| ISSN: | 0147-9571 |
| Popis: | In order to verify the role of immunosuppression in the pathogenesis of Bovine Viral Diarrhea Virus (BVDV) infection, two experiments have been carried out. In one experiment, calves previously infected with cytopathogenic (CP) or non-cytopathogenic (NCP) BVDV were treated with dexamethasone (DMS) 30 days later. In the other experiment, calves were simultaneously exposed to BVDV infection and to DMS treatment. In both experiments the DMS treated calves developed a more serious disease which in one calf was fatal. It was speculated that immunosuppression represents one of the most significant “key factors” in the occurrence of the bovine viral diarrhea/mucosal disease in cattle. |
| Databáze: | OpenAIRE |
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