Alternative parameters for echocardiographic assessment of fetal diastolic function

Autor: Luiz Henrique Soares Nicoloso, Eduardo Ioschpe Gus, R.T. Cardoso, Fabíola Satler, Paulo Zielinsky, Marlui Mesquita Scheid, Silvana Marcantonio, Antônio Piccoli, Jacira Pisani Zanettini, Cora Firpo, João Luiz Manica
Rok vydání: 2004
Předmět:
Physiology
Prenatal diagnosis
Pregnancy in Diabetics
Biochemistry
Pulmonary vein
Ventricular Dysfunction
Left
Pregnancy
General Pharmacology
Toxicology and Pharmaceutics
lcsh:QH301-705.5
Fetal diastolic function
lcsh:R5-920
medicine.diagnostic_test
General Neuroscience
Apnea
General Medicine
Echocardiography
Doppler
Pulmonary Veins
Cardiology
Female
Septum primum
medicine.symptom
lcsh:Medicine (General)
Fetal echocardiography
Ecocardiografia fetal
medicine.medical_specialty
Pregnancy Complications
Cardiovascular
Immunology
Biophysics
Ultrasonography
Prenatal
Fetal Heart
Internal medicine
Respiration
medicine
Humans
Analysis of Variance
Fetus
business.industry
Reproducibility of Results
Septum primum mobility
Cell Biology
Cardiomyopathy
Hypertrophic
Aspectos medicos legais [Pre-natal]
Surgery
Preload
Cross-Sectional Studies
lcsh:Biology (General)
Fetal pulmonary vein flow
Case-Control Studies
business
Zdroj: Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Brazilian Journal of Medical and Biological Research, Volume: 37, Issue: 1, Pages: 31-36, Published: JAN 2004
Brazilian Journal of Medical and Biological Research, Vol 37, Iss 1, Pp 31-36 (2004)
Brazilian Journal of Medical and Biological Research v.37 n.1 2004
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
ISSN: 0100-879X
DOI: 10.1590/s0100-879x2004000100005
Popis: Alternative methods to assess ventricular diastolic function in the fetus are proposed. Fetal myocardial hypertrophy in maternal diabetes was used as a model of decreased left ventricular compliance (LVC), and fetal respiratory movements as a model of increased LVC. Comparison of three groups of fetuses showed that, in 10 fetuses of diabetic mothers (FDM) with septal hypertrophy (SH), the mean excursion index of the septum primum (EISP) (ratio between the linear excursion of the flap valve and the left atrial diameter) was 0.36 +/- 0.09, in 8 FDM without SH it was 0.51 +/- 0.09 (P=0.001), and in the 8 normal control fetuses (NCF) it was 0.49 +/- 0.12 (P=0.003). In another study, 28 fetuses in apnea had a mean EISP of 0.39 +/- 0.05 which increased to 0.57 +/- 0.07 during respiration (P0.001). These two studies showed that the mobility of the septum primum was reduced when LVC was decreased and was increased when LVC was enhanced. Mean pulmonary vein pulsatility was higher in 14 FDM (1.83 +/- 1.21) than in 26 NCF (1.02 +/- 0.31; P=0.02). In the same fetuses, mean left atrial shortening was decreased (0.40 +/- 0.11) in relation to NCF (0.51 +/- 0.09; P=0.011). These results suggest that FDM may have a higher preload than normal controls, probably as a result of increased myocardial mass and LV hypertrophy. Prenatal assessment of LV diastolic function by fetal echocardiography should include analysis of septum primum mobility, pulmonary vein pulsatility, and left atrial shortening.
Databáze: OpenAIRE
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