ICTV Virus Taxonomy Profile: Deltavirus
| Autor: | Lars, Magnius, John, Taylor, William S, Mason, Camille, Sureau, Paul, Dény, Helene, Norder, Ictv Report Consortium |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Hepatitis B virus 030106 microbiology RNA polymerase II Genome Viral Virus Replication medicine.disease_cause Virus 03 medical and health sciences Viral Envelope Proteins Virology medicine Humans Virus classification Hepatitis biology RNA RNA Circular medicine.disease Hepatitis D 030104 developmental biology Rolling circle replication Helper virus Host-Pathogen Interactions biology.protein RNA Viral RNA Polymerase II Hepatitis Delta Virus Helper Viruses |
| Zdroj: | Journal of General Virology. 99:1565-1566 |
| ISSN: | 1465-2099 0022-1317 |
| DOI: | 10.1099/jgv.0.001150 |
| Popis: | Hepatitis delta virus, the only member of the only species in the genus Deltavirus, is a unique human pathogen. Its ~1.7 kb circular negative-sense RNA genome encodes a protein, hepatitis delta antigen, which occurs in two forms, small and large, both with unique functions. Hepatitis delta virus uses host RNA polymerase II to replicate via double rolling circle RNA synthesis. Newly synthesized linear RNAs are circularized after autocatalytic cleavage and ligation. Hepatitis delta virus requires the envelope of the helper virus, hepatitis B virus (family Hepadnaviridae), to produce infectious particles. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of Deltavirus which is available at www.ictv.global/report/deltavirus. |
| Databáze: | OpenAIRE |
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