Morphine action in grouped and isolated rats and mice

Autor:	Wojciech Rewerski, Andrzej Członkowski, Wojciech Kostowski, Tadeusz Piechocki
Rok vydání:	1977
Předmět:	Male Pharmacology Analgesic effect Time Factors Morphine business.industry Analgesic Pharmacology toxicology Social Environment Rats Aggression Analgesics Opioid Mice Social Isolation Opioid Threshold of pain Reaction Time medicine Animals Humans Hot plate business medicine.drug
Zdroj:	Psychopharmacology. 53:191-193
ISSN:	1432-2072 0033-3158
DOI:	10.1007/bf00426491
Popis:	The present study determines the analgesic effects of morphine in grouped and isolated rats and mice. Isolated animals developed altered behavioral patterns, including mouse-killing in rats and mutual aggressiveness in mice. The analgesic effect of morphine was tested by tail compression in rats and by the hot plate for mice. Isolated rats developing mouse-killing behavior had a raised pain threshold, while indifferent animals (nonkillers) responded less to morphine. Isolated mice, particularly low aggressors, gave enhanced responses to morphine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2629599c604463bb55b1deb72724daf7 https://doi.org/10.1007/bf00426491 Zobrazit plný text záznamu Full text from SpringerLink