Non-typhoidal Salmonella in Calabria, Italy: a laboratory and patient-based survey
| Autor: | Claudia Pileggi, Maria Rosaria Carullo, Pasquale Turno, Caterina Graziani, Yolande Therese Rose Proroga, Maria Pavia, Maria Crinò, Valentina Mascaro, Fabio Arigoni |
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| Přispěvatelé: | Mascaro, V, Pileggi, C, Crinò, M, Proroga, Ytr, Carullo, Mr, Graziani, C, Arigoni, F, Turno, P, Pavia, M |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Serotype Male Veterinary medicine Salmonella Epidemiology medicine.disease_cause Disease Outbreaks Ampicillin Drug Resistance Multiple Bacterial Surveys and Questionnaires Prevalence Medicine Child media_common education.field_of_study Incidence (epidemiology) General Medicine Middle Aged Antimicrobial Anti-Bacterial Agents Italy Child Preschool Salmonella Infections Female medicine.drug gastrointestinal infection Adult Diarrhea Adolescent 030106 microbiology Population salmonella Microbial Sensitivity Tests Microbiology 03 medical and health sciences Young Adult Antibiotic resistance media_common.cataloged_instance Humans European union Serotyping education Aged business.industry Research Infant Newborn Infant morbidity survey antimicrobial business |
| Zdroj: | BMJ Open |
| Popis: | IntroductionAlthough there has been a decrease in the number of cases of salmonellosis in the European Union, it still represents the primary cause of foodborne outbreaks. In Calabria region, data are lacking for the incidence of human non-typhoid salmonellosis as active surveillance has never been carried out.ObjectiveTo report the results of a laboratory and patient-based morbidity survey in Calabria to describe the incidence and distribution ofSalmonellaserovars isolated from humans, with a focus on antimicrobial resistance patterns.MethodsPositive cultures from human samples were collected from every laboratory participating in the surveillance, with a minimum set of information about each isolate. A questionnaire was then administered to the patients by telephone interview to assess the potential risk exposures.Salmonellaisolates underwent biochemical identification, molecular analysis by PCR and antimicrobial susceptibility testing by the disk-diffusion method.ResultsDuring a 2-year period, 105 strains ofSalmonellaspp were isolated from samples of patients with diarrhoea, with the highest isolation rate for children aged 1–5 years. The standardised rate was 2.7 cases per 1 00 000 population. The most commonSalmonellaisolates belonged to monophasic variant ofS.Typhimurium (S.4,[5],12:i:-) (33.3%), followed byS. Typhimurium (21.9%). 30.5% of the isolates were susceptible to all microbial agents tested and the most common pan-susceptible serotype wasS.Napoli (100%).S. 4,[5],12:i:- was resistant to ampicillin, streptomycin, sulfonamides and tetracyclines in 42.9% cases, while resistance to quinolones was seen in 14.3% of the isolates.ConclusionsThe results provide evidence that an active surveillance system effectively enhancesSalmonellanotifications. The high prevalence of antimicrobial resistance, including resistance to quinolones and multiresistance, enforces the need to strengthen strategies of surveillance and monitoring of antimicrobial use. |
| Databáze: | OpenAIRE |
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