Malignant Pancreatic Somatostatinoma in a Patient with Dermatitis herpetiformis and Coeliac Disease
| Autor: | I. Bjarnason, A. J. Levi, W. Murray, C.M. Swinson, J.M. Polak, S. Levi |
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| Rok vydání: | 1988 |
| Předmět: |
medicine.medical_specialty
Pathology Abdominal pain Dermatitis Herpetiformis medicine.medical_treatment Gastroenterology Streptozocin Coeliac disease Laparotomy Internal medicine Dermatitis herpetiformis Somatostatinoma medicine Humans business.industry nutritional and metabolic diseases Middle Aged Adenoma Islet Cell medicine.disease Malignant Somatostatinoma Pancreatic Neoplasms Celiac Disease medicine.anatomical_structure Malignant Pancreatic Somatostatinoma Female medicine.symptom Somatostatin Pancreas business |
| Zdroj: | Digestion. 39:1-6 |
| ISSN: | 1421-9867 0012-2823 |
| DOI: | 10.1159/000199601 |
| Popis: | A case of malignant somatostatinoma is reported in a patient with long-standing dermatitis herpetiformis and coeliac disease. The patient had non-specific abdominal pain of several years duration and came to attention because of weight loss despite strict adherence to a gluten-free diet. Plasma somatostatin levels were raised, and laparotomy showed a pancreatic tumour with metastases, which on histology, electron microscopy and immunohistochemistry proved to be a somatostatinoma. After a promising initial response to streptozotocin, she died 30 months later. This is the first reported occurrence of a somatostatinoma in a patient with coeliac disease, adding to the growing list of neoplastic complications in this condition. |
| Databáze: | OpenAIRE |
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