Safety of endovascular therapy for symptomatic intracranial artery stenosis: a national prospective registry
| Autor: | Xueli Cai, Tao Wang, Pengfei Wang, Zhao Jun, Zuoquan Chen, Huaizhang Shi, Tianxiao Li, Zhenwei Zhao, Osama O. Zaidat, Yongli Li, Qiong Cheng, Qinjian Sun, Adam A Dmytriw, Wei Wu, Xiaoxin Bai, Baijing Dong, Yang Zhang, Liyong Zhang, Wei Li, Yiling Cai, Yabing Wang, Hua Yang, Bo Hong, Liqun Jiao, Yujie Huang, Jie Lu, Maimai Ti, Jianfeng Chu, Jieqing Wan, Kun Yang, Qi Luo, Weiwen He |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Arterial stenosis business.industry medicine.medical_treatment Significant difference Angioplasty Endovascular Procedures Intracranial Artery Arteries Constriction Pathologic medicine.disease Endovascular therapy Surgery Stenosis medicine Clinical endpoint Humans Neurology. Diseases of the nervous system Neurology (clinical) Registries RC346-429 Cardiology and Cardiovascular Medicine business Stroke |
| Zdroj: | Stroke and Vascular Neurology, Vol, Iss |
| ISSN: | 2059-8696 |
| Popis: | IntroductionThe safety outcomes of endovascular therapy for intracranial artery stenosis in a real-world stetting are largely unknown. The Clinical Registration Trial of Intracranial Stenting for Patients with Symptomatic Intracranial Artery Stenosis (CRTICAS) was a prospective, multicentre, real-world registry designed to assess these outcomes and the impact of centre experience.Methods1140 severe, symptomatic intracranial arterial stenosis (ICAS) patients treated with endovascular therapy were included from 26 centres, further divided into three groups according to the annual centre volume of intracranial angioplasty and stent placement procedures over 2 years: (1) high volume for ≥25 cases/year; (2) moderate volume for 10–25 cases/year and (3) low volume for ResultsThe rate of 30-day stroke, transient ischaemic attack or death was 9.7% (111), with 5.4%, 21.1% and 9.7% in high-volume, moderate-volume and low-volume centres, respectively (pConclusionCompared with the preceding randomised controlled trials, this real-world, prospective, multicentre registry shows a lower complication rate of endovascular treatment for symptomatic ICAS. Non-uniform utilisation in endovascular technology, institutional experience and patient selection in different volumes of centres may have an impact on overall safety of this treatment. |
| Databáze: | OpenAIRE |
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