Off-Hour Primary Percutaneous Coronary Angioplasty Does Not Affect Outcome of Patients With ST-Segment Elevation Acute Myocardial Infarction Treated Within a Regional Network for Reperfusion
| Autor: | Paolo Ortolani, Marco Balducelli, Antonio Manari, Alberto Menozzi, Giuseppe Sangiorgi, Filippo Ottani, Gianni Casella, Andrea Santarelli, Antonio Marzocchi, Paolo Guastaroba, Rossana De Palma, Paolo Magnavacchi |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Percutaneous coronary intervention medicine.disease Interquartile range Angioplasty Internal medicine Conventional PCI Cardiology Medicine Platelet aggregation inhibitor ST segment Myocardial infarction business Cardiology and Cardiovascular Medicine TIMI |
| Zdroj: | JACC: Cardiovascular Interventions. 4(3):270-278 |
| ISSN: | 1936-8798 |
| DOI: | 10.1016/j.jcin.2010.11.012 |
| Popis: | Objectives This study aims to evaluate whether results of “off-hours” and “regular-hours” primary angioplasty (primary percutaneous coronary intervention [pPCI]) are comparable in an unselected population of patients with ST-segment elevation acute myocardial infarction treated within a regional network organization. Background Conflicting results exist on the outcome of off-hours pPCI. Methods We analyzed in-hospital and 1-year cardiac mortality among 3,072 consecutive ST-segment elevation myocardial infarction (STEMI) patients treated with pPCI between January 1, 2004, and June 30, 2006, during regular-hours (weekdays 8:00 am to 8:00 pm ) and off-hours (weekdays 8:01 pm to 7:59 am , weekends, and holidays) within the STEMI Network of the Italian Region Emilia-Romagna (28 hospitals: 19 spoke and 9 hub interventional centers). Results Fifty-three percent of patients were treated off-hours. Baseline findings were comparable, although regular-hours patients were older and had more incidences of multivessel disease. Median pain-to-balloon (195 min, interquartile range [IQR]: 140 to 285 vs. 186 min, IQR: 130 to 280 min; p = 0.03) and door-to-balloon time (88 min, IQR: 60 to 122 vs. 77 min, IQR: 48 to 116 min; p Conclusions When pPCI is performed within an efficient STEMI network focused on reperfusion, the clinical effectiveness of either off-hours or regular-hours pPCI is comparable. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|