A multicentered prospective analysis of diagnosis, risk factors, and outcomes associated with pediatric ventilator-associated pneumonia
Autor: | Sameer Gupta, Jeni Wincek, Brian Boville, Gloria Lukasiewicz, Rachel Blanton, Michael L. Forbes, Chunhong Bai |
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Rok vydání: | 2015 |
Předmět: |
Male
medicine.medical_specialty Adolescent MEDLINE Pneumonia ventilator associated Critical Care and Intensive Care Medicine Prospective analysis Risk Factors Prevalence Medicine Humans Multicenter Studies as Topic Hospital Mortality Prospective Studies Prospective cohort study Intensive care medicine Child business.industry Ventilator-associated pneumonia Infant Newborn Infant Pneumonia Ventilator-Associated Length of Stay medicine.disease Respiration Artificial Pneumonia Intensive Care Units Observational Studies as Topic Child Preschool Pediatrics Perinatology and Child Health Observational study Female business |
Zdroj: | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 16(3) |
ISSN: | 1529-7535 |
Popis: | To assess risk factors and outcomes associated with pediatric ventilator-associated pneumonia.Multicentered prospective observational cohort.Children's hospitals in the United States.Mechanically ventilated patients less than 18 years old.Prospective evaluation of the prevalence, risk factors, and outcomes of pediatric ventilator-associated pneumonia along with evaluation of diagnostic criterion for pediatric ventilator-associated pneumonia. The prevalence of pediatric ventilator-associated pneumonia was 5.2% (n = 2,082), for a rate of 7.1/1,000 ventilator days. Patients with ventilator-associated pneumonia had a longer unadjusted ICU length of stay (p0.0001) and increased length of mechanical ventilation by more than 11 days (p0.0001). After adjustment for patient factors, ICU length of stay (p = 0.03) and mechanical ventilation days (p = 0.001) remained significant. Patients with ventilator-associated pneumonia were almost three times more likely to die (p = 0.007). Independent risk factors for ventilator-associated pneumonia were reintubation and part-time ventilation.Pediatric ventilator-associated pneumonia is common in mechanically ventilated pediatric patients. These patients have longer length of stay, longer duration of mechanical ventilation, and increased risk for mortality. |
Databáze: | OpenAIRE |
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