Diabetes and pancreatic cancer: Exploring the two-way traffic
| Autor: | Raja Kalayarasan, Ayan Roy, Dukhabandhu Naik, Pazhanivel Mohan, Jayaprakash Sahoo, Sadishkumar Kamalanathan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Poor prognosis New onset diabetes Review Type 3c diabetes Risk Factors Internal medicine Diabetes mellitus Pancreatic cancer Elderly population Diabetes Mellitus medicine Humans Hypoglycemic Agents Risk factor Early Detection of Cancer Biochemical markers Aged business.industry Diabetes Gastroenterology General Medicine medicine.disease Pancreatic Neoplasms business Chronic pancreatitis Pancreatic adenocarcinoma After treatment |
| Zdroj: | World Journal of Gastroenterology |
| ISSN: | 1007-9327 |
| DOI: | 10.3748/wjg.v27.i30.4939 |
| Popis: | Pancreatic cancer (PC) is often associated with a poor prognosis. Long-standing diabetes mellitus is considered as an important risk factor for its development. This risk can be modified by the use of certain antidiabetic medications. On the other hand, new-onset diabetes can signal towards an underlying PC in the elderly population. Recently, several attempts have been made to develop an effective clinical tool for PC screening using a combination of history of new-onset diabetes and several other clinical and biochemical markers. On the contrary, diabetes affects the survival after treatment for PC. We describe this intimate and complex two-way relationship of diabetes and PC in this review by exploring the underlying pathogenesis. |
| Databáze: | OpenAIRE |
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